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D-glutamate cyclase

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D-glutamate cyclase
Identifiers
EC no.4.2.1.48
CAS no.37290-80-5
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The enzyme D-glutamate cyclase (EC 4.2.1.48) catalyzes the chemical reaction

D-glutamate {\displaystyle \rightleftharpoons } 5-oxo-Dproline + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming). This enzyme is also called D-glutamate hydro-lyase (cyclizing). This enzyme participates in D-glutamine and D-glutamate metabolism.

References

  • MEISTER A, BUKENBERGER MW, STRASSBURGER M (1963). "THE OPTICALLY-SPECIFIC ENZYMATIC CYCLIZATION OF D-GLUTAMATE". Biochem. Z. 338: 217–29. PMID 14087295.
Carbon–oxygen lyases (EC 4.2) (primarily dehydratases)
4.2.1: Hydro-Lyases
4.2.2: Acting on polysaccharides
4.2.3: Acting on phosphates
4.2.99: Other
Enzymes
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