DRI or D.R.I. may stand for:
Business
- DRI, the NYSE stock symbol for Darden Restaurants, Inc.
- Digital Research Inc, first large software company in the business for microcomputers
- Data Resources Inc., a former distributor of economic data, now part of IHS Global Insight
- Diamond Resorts International Inc. a vacation ownership company
Computing
- Declarative referential integrity, in databases
- Direct Rendering Infrastructure, a software interface
Government
- United States District Court for the District of Rhode Island
- Directorate of Revenue Intelligence, Intelligence Agency of India
Healthcare and bioscience
- Dietary Reference Intake, dietary recommendation
- Doncaster Royal Infirmary, South Yorkshire, UK
- Dopamine reuptake inhibitor, class of drugs
- Former Dundee Royal Infirmary, Scotland, UK
Other organisations
- Desert Research Institute, environmental research
- Direct Relief, health NGO
- Directly Responsible Individual, Project specific title in Apple Computer's Corporate ecosystem.
Other
- Direct reduced iron, used in steel production
- D.R.I. (band), Dirty Rotten Imbeciles, an American crossover thrash band
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