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Debayan Dasgupta is an Indian scientist, entrepreneur, and engineer known for his work in nanorobotics and magnetic helical microstructures. He is the co-founder of Theranautilus, considered the world's first nanorobotics company focused on clinical applications.

Early Life and Education

Dasgupta completed his Bachelor of Engineering in Electronics and Communications in 2013. He subsequently pursued his higher education at the Indian Institute of Science (IISc), where he completed his MS in Engineering (Nanoscience and Engineering) in 2017, followed by a PhD in Engineering in 2021. His doctoral thesis, titled "Applications of magnetic helical nanomotors: From Cancer biology to Dentistry," received the Best Thesis Award.

Scientific career

Dasgupta's research has focused on the development and application of magnetic helical microstructures for medical applications, particularly in drug delivery and local microrheology. His work has included the design of instruments for deep-tissue imaging and the development of novel methods for maneuvering microscale structures through tissue-like environments.

Research Contributions

His scientific work has been published in several high-impact journals, including:

Advanced Healthcare Materials Angewandte Chemie International Edition Journal of Physics: Condensed Matter Advanced Functional Materials

Patents

Dasgupta holds several patents in the field of nanorobotics and microscopic particle control:

Nanostructure, nanocomposite, and implementations thereof (PCT/IN2023/050384) Methods for controlling motion of magnetically-driven microscopic particles (US20220226073A1) Locomotion methods for nanorobots and their implementations (US20220273382A1) Charge-based methods for studying biochemical microenvironments (Indian Patent: 201941042707)

Entrepreneurship

In October 2020, Dasgupta co-founded Theranautilus, a startup focused on commercializing magnetic nanorobots for clinical applications. Under his leadership as CTO, the company has developed a medical device that completed animal trials and is currently undergoing ISO certification. The company has secured funding through CSR initiatives, grants, and equity. Debayan is recognised as a Falling Walls Emerging talent.

Awards and Recognition

Theranautilus has received several notable awards including:

• National Startup Award
• Board of Innovator's Top 10 Medical Startups

Technical Expertise

Dasgupta possesses extensive experience in:

Scientific programming (Python, MATLAB, SQL) Advanced microscopy techniques Magnetic systems and hyperthermia Various deposition techniques (Chemical Vapor Deposition, Physical Vapor Deposition) Nanofabrication and clean room operations Scientific visualization and data analysis

References

1. Dasgupta, Debayan; Peddi, Shanmukh; Saini, Deepak Kumar; Ghosh, Ambarish (2022-05-04). "Mobile Nanobots for Prevention of Root Canal Treatment Failure". Advanced Healthcare Materials. 11 (14): 2200232. doi:10.1002/adhm.202200232. ISSN 2192-2640. PMC 7613116. PMID 35481942.
2. Dasgupta, D.; Pally, D.; Saini, D.; Bhat, R.; Ghosh, A. (2020). "Nanomotors Sense Local Physicochemical Heterogeneities in Tumor Microenvironments*". Angewandte Chemie International Edition. 59 (52): 23690–23696. doi:10.1002/anie.202008681. PMC 7756332. PMID 32918839.
3. Pal, M.; Dasgupta, D. (2020). "Helical nanobots as mechanical probes of intra- and extracellular environments". Journal of Physics: Condensed Matter. 32 (22). doi:10.1088/1361-648X/ab6f89. PMID 31978922.
4. Ghosh, Arijit; Dasgupta, Debayan; Pal, Malay; Morozov, Konstantin I.; Leshansky, Alexander M.; Ghosh, Ambarish (June 2018). "Helical Nanomachines as Mobile Viscometers". Advanced Functional Materials. 28 (25): 1705687. doi:10.1002/adfm.201705687.
5. "Falling Walls".
6. "National Technology Day celebrations highlight surge in entrepreneurship spirit for cost effective tech". pib.gov.in.
7. "Top 10 med-tech companies solving real health challenges". February 16, 2023.

• Indian scientists
• Nanotechnologists
• Indian Institute of Science alumni
• Living people