Derp may refer to:
- Mr. Derp, a minor character in South Park, a show that popularized the Internet slang word derp
- Drug Effectiveness Review Project
- D.E.R.P., a robot character seen in the Fresh Beat Band of Spies episode "Dance Bots"
- "Derp", a track released in 2014 by Bassjackers and MAKJ
- Derp (hacker group), also known as Derptrolling, a former hacker group
See also
- D'Erp Castle, the Netherlands
- Darp, a town in the Netherlands
- Derpy, a background character in My Little Pony: Friendship Is Magic
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