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Dichapetalins

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Small class of triterpenoid compounds
Dichapetalin A

Dichapetalins are a small class of triterpenoid compounds found primarily in the Dichapetalaceae family but also reportedly in Phyllanthus (Euphorbiaceae). They are structural derivatives of dammarene characterized by a C6C2 unit connected to a dammarene or a 13,30-cyclodammarane skeleton with variable C-17 side chains containing actone, spirolactone, lactol, acetal, or furan moieties. They have been found to display cytotoxicity against several cancer cell lines.

References

  1. Tuchinda, Patoomratana; Kornsakulkarn, Jittra; Pohmakotr, Manat; Kongsaeree, Palangpon; Prabpai, Samran; Yoosook, Chalobon; Kasisit, Jitra; Napaswad, Chanita; Sophasan, Samaisukh; Reutrakul, Vichai (April 2008). "Dichapetalin-Type Triterpenoids and Lignans from the Aerial Parts ofPhyllanthus acutissima". Journal of Natural Products. 71 (4): 655–663. doi:10.1021/np7007347. ISSN 0163-3864. PMID 18271551.
  2. Jing, Shu-Xi; Luo, Shi-Hong; Li, Chun-Huan; Hua, Juan; Wang, Yan-Li; Niu, Xue-Mei; Li, Xiao-Nian; Liu, Yan; Huang, Chun-Shuai; Wang, Ying; Li, Sheng-Hong (2014-03-05). "Biologically Active Dichapetalins from Dichapetalum gelonioides". Journal of Natural Products. 77 (4): 882–893. doi:10.1021/np400971r. ISSN 0163-3864. PMID 24597894.


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