Dichlorophen - Misplaced Pages

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Dichlorophen
Clinical data


AHFS/Drugs.com	International Drug Names
ATC code	P02DX02 (WHO)
Identifiers
IUPAC name 4-Chloro-2-phenol
CAS Number	97-23-4
PubChem CID	3037
ChemSpider	2929
UNII	T1J0JOU64O
KEGG	C14292
ChEMBL	ChEMBL33845
CompTox Dashboard (EPA)	DTXSID6021824
ECHA InfoCard	100.002.335
Chemical and physical data
Formula	C₁₃H₁₀Cl₂O₂
Molar mass	269.12 g·mol
3D model (JSmol)	Interactive image
Density	1.5 g/cm g/cm
Melting point	177.5 °C (351.5 °F)
Solubility in water	0.003 g/100 mL mg/mL (20 °C)
SMILES C1=CC(=C(C=C1Cl)CC2=C(C=CC(=C2)Cl)O)O
InChI InChI=1S/C13H10Cl2O2/c14-10-1-3-12(16)8(6-10)5-9-7-11(15)2-4-13(9)17/h1-4,6-7,16-17H,5H2 Key:MDNWOSOZYLHTCG-UHFFFAOYSA-N
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Dichlorophen is an anticestodal agent, fungicide, germicide, and antimicrobial agent. It is used in combination with toluene for the removal of parasites such as ascarids, hookworms, and tapeworms from dogs and cats.

Safety and regulation

LD50 (oral, mouse) is 3300 mg/kg.

Lide DR (1998). Handbook of Chemistry and Physics (87 ed.). Boca Raton, Florida: CRC Press. pp. 8–118. ISBN 0-8493-0594-2.
Milne, G.W.A. (Ed.). (2005). Gardner's commercially important chemicals: Synonyms, trade names, and properties. Hoboken, N.J.: Wiley-Interscience. Google Books
"Code of Federal Regulations", Code of Federal Regulations, Title 21, Volume 6, U.S. Government Printing Office, 2005-04-01, retrieved 2009-05-01
Fiege H, Voges HW, Hamamoto T, Umemura S, Iwata T, Miki H, Fujita Y, Buysch HJ, Garbe D, Paulus W (2007). "Phenol Derivatives". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a19_313. ISBN 978-3527306732.

Binds tubulin	benzimidazole Triclabendazole
AChE inhibitor	phosphonic acid Metrifonate
Other/unknown	quinoline Arpraziquantel Praziquantel (+esafoxolaner/eprinomectin) Oxamniquine phenol Bithionol thiazole Niridazole thioxanthone Hycanthone Lucanthone antimony compounds Stibophen Tartar emetic

Binds tubulin	benzimidazole Albendazole
Other/unknown	quinoline Praziquantel (+esafoxolaner/eprinomectin) salicylanilide Niclosamide aminoacridine Quinacrine butyrophenone Desaspidin chlorophenol Dichlorophen

Binds tubulin	benzimidazole Mebendazole Albendazole Tiabendazole Fenbendazole Ciclobendazole Flubendazole
Glutamate-gated chloride channel, GABA receptor	avermectins Abamectin Doramectin Emamectin Eprinomectin (+esafoxolaner/praziquantel) Ivermectin Selamectin milbemycins Moxidectin (+fluralaner) Milbemycin oxime
NMDA	tetrahydropyrimidine Pyrantel pyrantel pamoate Oxantel Morantel Carbantel Febantel (aka felsantel)
Other/unknown	piperazine Piperazine Diethylcarbamazine thiazole Levamisole quinolinium Pyrvinium benzylammonium Bephenium naphthalenesulfonate Suramin Ascaridole Hexylresorcinol Santonin Tribendimidine Tetrachloroethylene

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