Diego Valdés or Valdez may refer to:
- Diego Valdés (athlete) (born 1983), Chilean Olympic sprinter
- Diego Valdés (Colombian footballer) (born 1981), Colombian football midfielder
- Diego Valdés (Chilean footballer) (born 1994), Chilean football midfielder
- Diego Valdez (Paraguayan footballer) (born 1993), or Mudo Valdez, Paraguayan football midfielder
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