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Galactitol

Names
IUPAC name D-Galactitol
Systematic IUPAC name (2R,3S,4R,5S)-hexane-1,2,3,4,5,6-hexol
Other names Dulcitol
Identifiers
CAS Number	608-66-2
3D model (JSmol)	Interactive image
ChEBI	CHEBI:16813
ChEMBL	ChEMBL1773904
ChemSpider	11357
ECHA InfoCard	100.009.242
PubChem CID	11850
UNII	113ZQ1Y7DD
CompTox Dashboard (EPA)	DTXSID1046051
InChI InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5+,6-Key: FBPFZTCFMRRESA-GUCUJZIJSA-N InChI=1/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5+,6-Key: FBPFZTCFMRRESA-GUCUJZIJBM
SMILES O((O)CO)(O)(O)CO
Properties
Chemical formula	C6H14O6
Molar mass	182.172 g/mol
Magnetic susceptibility (χ)	-112.40·10 cm/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). N verify (what is  ?) Infobox references

Galactitol (dulcitol) is a sugar alcohol, the reduction product of galactose. It has a slightly sweet taste. In people with galactokinase deficiency, a form of galactosemia, excess dulcitol forms in the lens of the eye leading to cataracts.

Galactitol is produced from galactose in a reaction catalyzed by aldose reductase.

The other common galactose metabolism defect is a defect in galactose-1-phosphate uridylyltransferase, an autosomal recessive disorder, which also causes a buildup of galactitol as a result of increased concentrations of galactose-1-phosphate and galactose. This disorder leads to cataracts caused by galactitol buildup.

References

1. ^ "Galactitol - Compound Summary". National Center for Biotechnology Information. Retrieved 2008-08-06.
2. Roth, KS (September 10, 2007). "Galactokinase Deficiency". eMedicine. WebMD. Retrieved 2008-08-08.

External links

• Media related to Galactitol at Wikimedia Commons

• Sugar alcohols
• Sugar substitutes