Misplaced Pages

EID1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4NUF
Identifiers
Aliases	EID1, C15orf3, CRI1, EID-1, IRO45620, PTD014, RBP21, PNAS-22, EP300 interacting inhibitor of differentiation 1
External IDs	OMIM: 605894; MGI: 1889651; HomoloGene: 49376; GeneCards: EID1; OMA:EID1 - orthologs
Gene location (Human) Chr. Chromosome 15 (human) Band 15q21.1 Start 48,878,134 bp End 48,880,173 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2|2 F1 Start 125,515,015 bp End 125,516,705 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tendon of biceps brachii Achilles tendon germinal epithelium right ventricle internal globus pallidus seminal vesicula superficial temporal artery ganglionic eminence retinal pigment epithelium myocardium Top expressed in barrel cortex dorsomedial hypothalamic nucleus Gonadal ridge median eminence human fetus fossa atrium habenula condyle subiculum More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding histone acetyltransferase binding transcription corepressor activity histone acetyltransferase regulator activity Cellular component cytoplasm nucleus nucleoplasm cytoplasmic ribonucleoprotein granule Biological process cell cycle cell differentiation negative regulation of transcription, DNA-templated regulation of transcription, DNA-templated transcription, DNA-templated negative regulation of transcription by RNA polymerase II regulation of histone acetylation regulation of cell differentiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23741 58521 Ensembl ENSG00000255302 ENSMUSG00000091337 UniProt Q9Y6B2 Q9DCR4 RefSeq (mRNA) NM_014335 NM_025613 RefSeq (protein) NP_055150 NP_079889 Location (UCSC) Chr 15: 48.88 – 48.88 Mb Chr 2: 125.52 – 125.52 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

EP300-interacting inhibitor of differentiation 1 is a protein that in humans is encoded by the EID1 gene.

Interactions

EID1 has been shown to interact with EP300 and Retinoblastoma protein.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000255302 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000091337 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Carim L, Sumoy L, Andreu N, Estivill X, Escarceller M (June 2000). "Identification and expression analysis of C15orf3, a novel gene on chromosome 15q21.1→q21.2". Cytogenet Cell Genet. 88 (3–4): 330–2. doi:10.1159/000015523. PMID 10828624. S2CID 27139235.
6. ^ MacLellan WR, Xiao G, Abdellatif M, Schneider MD (December 2000). "A novel Rb- and p300-binding protein inhibits transactivation by MyoD". Mol Cell Biol. 20 (23): 8903–15. doi:10.1128/MCB.20.23.8903-8915.2000. PMC 86545. PMID 11073990.
7. "Entrez Gene: EID1 EP300 interacting inhibitor of differentiation 1".
8. ^ Miyake, S; Sellers W R; Safran M; Li X; Zhao W; Grossman S R; Gan J; DeCaprio J A; Adams P D; Kaelin W G (December 2000). "Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle". Mol. Cell. Biol. 20 (23): 8889–902. doi:10.1128/MCB.20.23.8889-8902.2000. ISSN 0270-7306. PMC 86544. PMID 11073989.

Further reading

• Ghosh AK, Varga J (2007). "The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis". J. Cell. Physiol. 213 (3): 663–71. doi:10.1002/jcp.21162. PMID 17559085. S2CID 41744258.
• Margottin F, Bour SP, Durand H, et al. (1998). "A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif". Mol. Cell. 1 (4): 565–74. doi:10.1016/S1097-2765(00)80056-8. PMID 9660940.
• Miyake S, Sellers WR, Safran M, et al. (2000). "Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle". Mol. Cell. Biol. 20 (23): 8889–902. doi:10.1128/MCB.20.23.8889-8902.2000. PMC 86544. PMID 11073989.
• Wen H, Ao S (2001). "Identification and characterization of a novel human cDNA encoding a 21 kDa pRb-associated protein". Gene. 263 (1–2): 85–92. doi:10.1016/S0378-1119(00)00585-0. PMID 11223246.
• Båvner A, Johansson L, Toresson G, et al. (2002). "A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP". EMBO Rep. 3 (5): 478–84. doi:10.1093/embo-reports/kvf087. PMC 1084100. PMID 11964378.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ledl A, Schmidt D, Müller S (2005). "Viral oncoproteins E1A and E7 and cellular LxCxE proteins repress SUMO modification of the retinoblastoma tumor suppressor". Oncogene. 24 (23): 3810–8. doi:10.1038/sj.onc.1208539. PMID 15806172.
• Krützfeldt M, Ellis M, Weekes DB, et al. (2005). "Selective ablation of retinoblastoma protein function by the RET finger protein". Mol. Cell. 18 (2): 213–24. doi:10.1016/j.molcel.2005.03.009. PMID 15837424.
• Benevolenskaya EV, Murray HL, Branton P, et al. (2005). "Binding of pRB to the PHD protein RBP2 promotes cellular differentiation". Mol. Cell. 18 (6): 623–35. doi:10.1016/j.molcel.2005.05.012. PMID 15949438.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

This protein-related article is a stub. You can help Misplaced Pages by expanding it.

• v
• t
• e

• Genes on human chromosome 15
• Protein stubs