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EMP1
Identifiers
Aliases	EMP1, CL-20, EMP-1, TMP, epithelial membrane protein 1
External IDs	OMIM: 602333; MGI: 107941; HomoloGene: 1088; GeneCards: EMP1; OMA:EMP1 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) Band 12p13.1 Start 13,196,723 bp End 13,219,941 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band 6 G1|6 66.25 cM Start 135,339,543 bp End 135,360,171 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of pharynx oral cavity amniotic fluid synovial joint body of tongue gums gingival epithelium buccal mucosa cell skin of hip stromal cell of endometrium Top expressed in corneal stroma conjunctival fornix umbilical cord skin of external ear ankle joint left lung lobe skin of back stroma of bone marrow dermis sciatic nerve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component plasma membrane membrane integral component of membrane Biological process multicellular organism development bleb assembly cell population proliferation cell death epidermis development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2012 13730 Ensembl ENSG00000134531 ENSMUSG00000030208 UniProt P54849 P47801 RefSeq (mRNA) NM_001423 NM_001288627 NM_001288628 NM_010128 RefSeq (protein) NP_001414 NP_001275556 NP_001275557 NP_034258 Location (UCSC) Chr 12: 13.2 – 13.22 Mb Chr 6: 135.34 – 135.36 Mb PubMed search
Wikidata
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Epithelial membrane protein 1 is a protein that in humans is encoded by the EMP1 gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000134531 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000030208 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ben-Porath I, Benvenisty N (Feb 1997). "Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins". Gene. 183 (1–2): 69–75. doi:10.1016/S0378-1119(96)00475-1. PMID 8996089.
6. Chen Y, Medvedev A, Ruzanov P, Marvin KW, Jetten AM (May 1997). "cDNA cloning, genomic structure, and chromosome mapping of the human epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22 family". Genomics. 41 (1): 40–8. doi:10.1006/geno.1997.4524. PMID 9126480.
7. "Entrez Gene: EMP1 epithelial membrane protein 1".

Further reading

• Jain A, Tindell CA, Laux I, et al. (2005). "Epithelial membrane protein-1 is a biomarker of gefitinib resistance". Proc. Natl. Acad. Sci. U.S.A. 102 (33): 11858–63. Bibcode:2005PNAS..10211858J. doi:10.1073/pnas.0502113102. PMC 1187965. PMID 16087880.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wang HT, Kong JP, Ding F, et al. (2003). "Analysis of gene expression profile induced by EMP-1 in esophageal cancer cells using cDNA Microarray". World J. Gastroenterol. 9 (3): 392–8. doi:10.3748/wjg.v9.i3.392. PMC 4621547. PMID 12632483.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Wang HT, Liu ZH, Wang XQ, Wu M (2003). "". AI Zheng. 21 (3): 229–32. PMID 12451984.
• Liehr T, Kuhlenbäumer G, Wulf P, et al. (1999). "Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3". Genomics. 58 (1): 106–8. doi:10.1006/geno.1999.5803. PMID 10331954.
• Schiemann S, Rückels M, Engelholm LH, et al. (1997). "Differential gene expression in human mammary carcinoma cells: identification of a new member of a receptor family". Anticancer Res. 17 (1A): 13–20. PMID 9066625.
• Lobsiger CS, Magyar JP, Taylor V, et al. (1997). "Identification and characterization of a cDNA and the structural gene encoding the mouse epithelial membrane protein-1". Genomics. 36 (3): 379–87. doi:10.1006/geno.1996.0482. PMID 8884260.
• Ruegg CL, Wu HY, Fagnoni FF, et al. (1996). "B4B, a novel growth-arrest gene, is expressed by a subset of progenitor/pre-B lymphocytes negative for cytoplasmic mu-chain". J. Immunol. 157 (1): 72–80. doi:10.4049/jimmunol.157.1.72. PMID 8683158. S2CID 13361245.
• Marvin KW, Fujimoto W, Jetten AM (1996). "Identification and characterization of a novel squamous cell-associated gene related to PMP22". J. Biol. Chem. 270 (48): 28910–6. doi:10.1074/jbc.270.48.28910. PMID 7499420.

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