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Efferent nerve fiber
In the peripheral nervous system, afferent and efferent projections are always from the perspective of the spinal cord.
Details
System	Peripheral nervous system
Identifiers
Latin	neurofibrae efferentes
TA98	A14.2.00.018
TH	H2.00.06.1.00016
FMA	76571
Anatomical terms of neuroanatomy[edit on Wikidata]

Efferent nerve fibers are the axons of efferent neurons that exit a particular region. These terms have a slightly different meaning in the context of the peripheral nervous system (PNS) and central nervous system (CNS). The efferent fiber is a long process projecting far from the neuron's body that carries nerve impulses away from the central nervous system toward the peripheral effector organs (muscles and glands). A bundle of these fibers constitute an efferent nerve. The opposite direction of neural activity is afferent conduction, which carries impulses by way of the afferent nerve fibers of sensory neurons.

In the nervous system, there is a "closed loop" system of sensation, decision, and reactions. This process is carried out through the activity of sensory neurons, interneurons, and motor neurons.

In the CNS, afferent and efferent projections can be from the perspective of any given brain region. That is, each brain region has its own unique set of afferent and efferent projections. In the context of a given brain region, afferents are arriving fibers while efferents are exiting fibers.

Structure

Motor nerve

The efferent nerve fibers of motor neurons are involved in muscle control, both skeletal and smooth muscle. The cell body of the motor neuron is connected to a single, long axon and several shorter dendrites projecting out of the cell body itself. This axon then forms a neuromuscular junction with the effectors. The cell body of the motor neuron is satellite-shaped. The motor neuron is present in the grey matter of the spinal cord and medulla oblongata, and forms an electrochemical pathway to the effector organ or muscle. Besides motor nerves, there are efferent sensory nerves that often serve to adjust the sensitivity of the signal relayed by the afferent sensory nerve.

Types

There are three types of efferent fibers: general somatic efferent fibers (GSE), general visceral efferent fibers (GVE) and special visceral efferent fibers (SVE).

Subtypes of general somatic efferent fibers include: alpha motor neurons (α) – these target extrafusal muscle fibers, and gamma motor neurons (γ) that target intrafusal muscle fibers. Beta motor neurons target both types of muscle fiber and there are two types known as static and dynamic.

Etymology and mnemonics

Both afferent and efferent come from French, evolved from Latin (the basis of many terms in medicine and biology) for the terms, respectively, ad ferens (Latin verb ferre: carry), meaning carrying into, and ex ferens, meaning carrying away (ad literally means to, and e = ex means from). Ad and ex give an easy mnemonic device for remembering the relationship between afferent and efferent: afferent connection arrives and an efferent connection exits.

Afferent and efferent are connected to affect and effect through their common Latin roots: Afferent nerves affect the subject, whereas efferent nerves allow the subject to effect change.

See also

• Sensory nerve
• Motor nerve
• Afferent nerve fiber
• Sensory neuron
• Motor neuron (efferent neuron)

References

1. "Efferent nerve fibre | anatomy | Britannica". www.britannica.com. Retrieved May 13, 2024.
2. Mader S. S. (2000): Human biology. McGraw-Hill, New York, ISBN 0-07-290584-0; ISBN 0-07-117940-2.
3. Hall J. E., Guyton A. C. (2006): Textbook of medical physiology, 11th edition. Elsevier Saunders, St. Louis, Mo, ISBN 0-7216-0240-1.
4. Warrell D. A., Cox T. M., Firth J. D. (2010): The Oxford Textbook of Medicine Archived 2012-03-21 at the Wayback Machine (5th ed.). Oxford University Press
5. MedicalMnemonics.com: 3502 3463 367 115

• Peripheral nervous system
• Medical mnemonics