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From the posterior wall of the saccule a canal, the endolymphatic duct, is given off; this duct is joined by the utriculosaccular duct, and then passes along the vestibular aqueduct and ends in a blind pouch, the endolymphatic sac, on the posterior surface of the petrous portion of the temporal bone, where it is in contact with the dura mater. Studies suggest that the endolymphatic duct and endolymphatic sac perform both absorptive and secretory, as well as phagocytic and immunodefensive, functions.

Neoplasms of the endolymphatic sac are very rare tumors.

References

This article incorporates text in the public domain from page 1052 of the 20th edition of Gray's Anatomy (1918)

1. Schuknecht HF. Pathology of the Ear. Philadelphia, Pa: Lea & Febiger; 1993:45–47, 50–51, 62, 64, 101
2. Wackym, P. A.; Friberg, U.; Bagger-Sjöbäck, D.; Linthicum, F. H.; Friedmann, I.; Rask-Andersen, H. (August 1987). "Human endolymphatic sac: possible mechanisms of pressure regulation". The Journal of Laryngology and Otology. 101 (8): 768–779. doi:10.1017/s0022215100102713. ISSN 0022-2151. PMID 3655528.
3. Yeo, S. W.; Gottschlich, S.; Harris, J. P.; Keithley, E. M. (June 1995). "Antigen diffusion from the perilymphatic space of the cochlea". The Laryngoscope. 105 (6): 623–628. doi:10.1288/00005537-199506000-00012. ISSN 0023-852X. PMID 7769947.
4. Rask-Andersen, H.; Danckwardt-Lillieström, N.; Linthicum, F. H.; House, W. F. (February 1991). "Ultrastructural evidence of a merocrine secretion in the human endolymphatic sac". The Annals of Otology, Rhinology, and Laryngology. 100 (2): 148–156. doi:10.1177/000348949110000211. ISSN 0003-4894. PMID 1992902.
5. Fukazawa, K.; Sakagami, M.; Matsunaga, T.; Fujita, H. (July 1991). "Endocytotic activity of the free floating cells and epithelial cells in the endolymphatic sac: an electron microscopic study". The Anatomical Record. 230 (3): 425–433. doi:10.1002/ar.1092300315. ISSN 0003-276X. PMID 1867416.
6. Wackym, P. A.; Friberg, U.; Linthicum, F. H.; Bagger-Sjöbäck, D.; Bui, H. T.; Hofman, F.; Rask-Andersen, H. (May–June 1987). "Human endolymphatic sac: morphologic evidence of immunologic function". The Annals of Otology, Rhinology, and Laryngology. 96 (3 Pt 1): 276–281. doi:10.1177/000348948709600308. ISSN 0003-4894. PMID 3300505.

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