| Enteric glia | |
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| Anatomical terminology[edit on Wikidata] |
The enteric glia, enteric glial cells or EGCs are a population of neuroglial cells that populate the enteric nervous system.
These cells are one of the major neural-crest-derived cell lineages, found throughout the gastrointestinal tract. The enteric glial cells play a variety of roles, such as modulating nociception (pain sensation), exerting immune functions, and coordingating gastrointestinal motility. They are the largest glial population outside the brain, and considered "a key node of the gut-brain axis".
References
- ^ Liu, Chang; Yang, Jing (2022-04-28). "Enteric Glial Cells in Immunological Disorders of the Gut". Frontiers in Cellular Neuroscience. 16. doi:10.3389/fncel.2022.895871. ISSN 1662-5102. PMC 9095930. PMID 35573829.
- Morales-Soto, Wilmarie; Gonzales, Jacques; Jackson, William F.; Gulbransen, Brian D. (2023-11-21). "Enteric glia promote visceral hypersensitivity during inflammation through intercellular signaling with gut nociceptors". Science Signaling. 16 (812): eadg1668. doi:10.1126/scisignal.adg1668. ISSN 1945-0877. PMC 10733972. PMID 37988454.
- Scavuzzo, Marissa A.; Letai, Katherine C.; Maeno-Hikichi, Yuka; Wulftange, William J.; Shah, Isha K.; Rameshbabu, Jeyashri S.; Tomar, Alka; Shick, H. Elizabeth; Shah, Aakash K.; Xiong, Ying; Cohn, Erin F.; Allan, Kevin C.; Tesar, Paul J. (2023-06-09). "Enteric glial hub cells coordinate intestinal motility". bioRxiv: 2023.06.07.544052. doi:10.1101/2023.06.07.544052. PMC 10274798. PMID 37333182.
- Rosenberg, Harry J.; Rao, Meenakshi (August 2021). "Enteric glia in homeostasis and disease: From fundamental biology to human pathology". iScience. 24 (8): 102863. Bibcode:2021iSci...24j2863R. doi:10.1016/j.isci.2021.102863. ISSN 2589-0042. PMC 8348155. PMID 34401661.
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