Eosinophilic (Greek suffix -phil-, meaning loves eosin) is the staining of tissues, cells, or organelles after they have been washed with eosin, a dye.
Eosin is an acidic dye for staining cell cytoplasm, collagen, and muscle fibers. Eosinophilic describes the appearance of cells and structures seen in histological sections that take up the staining dye eosin. Such eosinophilic structures are, in general, composed of protein.
Eosin is usually combined with a stain called hematoxylin to produce a hematoxylin- and eosin-stained section (also called an H&E stain, HE or H+E section). It is the most widely used histological stain for a medical diagnosis. When a pathologist examines a biopsy of a suspected cancer, they will stain the biopsy with H&E.
Some structures seen inside cells are described as being eosinophilic; for example, Lewy and Mallory bodies. Some cells are also described as eosinophilic, such as Leukocytes.
See also
- Basophilic (affinity to hematoxylin)
- Eosinophil
- Eosinophilia
- Eosinophilic meningitis
- Acidophile (histology)
References
- Tubbs, R. Shane; Rizk, Elias; Shoja, Mohammadali; Loukas, Marios; Barbaro, Nicholas; Spinner, Robert J. (2015). Nerves and Nerve Injuries: Vol 1: History, Embryology, Anatomy, Imaging, and Diagnostics. Academic Press. p. 84. ISBN 978-0-12-410447-1.
- ^ Sharma, Sonal; Khanna, Geetika (2019). Textbook of Pathology and Genetics for Nurses E-Book. Elsevier Health Sciences. p. 9. ISBN 978-8-13-125538-4.
- ^ Leong, Franz Joel; Dartois, Veronique; Dick, Thomas (2016). A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis. CRC Press. p. 199. ISBN 978-1-43-983530-2.
- Eosinophilic. Medline Plus. Accessed March 2nd, 2012.
- Dixon, Frank J. (1986). Advances in Immunology, Volume 39. Academic Press. p. 323. ISBN 9780120224395.
_histopatholgy.jpg){kind=small} | This article related to pathology is a stub. You can help Misplaced Pages by expanding it. |