Epperly may refer to:
- Epperly, West Virginia, United States, an unincorporated community in Raleigh County
- Mount Epperly, in Antarctica
People
- Al Epperly (1918–2003), American baseball player
- Bruce G. Epperly (born 1953), American theologian
- Jillian Mai Thi Epperly (born c. 1973/4), creator of Jilly Juice
- Quin Epperly (1913–2001), American race car builder
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