F80 may refer to:
Vehicles
- Aircraft
- Farman F.80, a French biplane
- Lockheed F-80 Shooting Star, an American jet fighter
- UL-Jih F80 Fascination, a Czech ultralight
- Automobiles
- BMW F80, a German high performance sedan
- Toyota Kijang (F80), a Japanese multi purpose vehicle
- Ferrari F80, limited production sports car built by Italian automotive manufacturer Ferrari
- Ships
- HMS Duncan (F80), a Blackwood-class frigate of the Royal Navy
- HMS Grafton (F80) a Type 23 frigate of the Royal Navy
- HMS Torrid (1917), an R-class destroyer of the Royal Navy
- HMS Woolwich (F80), a destroyer tender of the Royal Navy
Other uses
- Nikon F80, a SLR camera also known as the Nikon N80
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