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FTSJ3

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Class of enzymes
FTSJ3
Identifiers
AliasesFTSJ3, EPCS3, SPB1, FtsJ homolog 3, FtsJ RNA methyltransferase homolog 3, FtsJ RNA 2'-O-methyltransferase 3
External IDsOMIM: 618411; MGI: 1860295; HomoloGene: 5451; GeneCards: FTSJ3; OMA:FTSJ3 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)
Chromosome 17 (human)Genomic location for FTSJ3Genomic location for FTSJ3
Band17q23.3Start63,819,433 bp
End63,830,012 bp
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)
Chromosome 11 (mouse)Genomic location for FTSJ3Genomic location for FTSJ3
Band11 E1|11 68.89 cMStart106,139,968 bp
End106,146,905 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • granulocyte

  • sural nerve

  • tendon of biceps brachii

  • stromal cell of endometrium

  • gastric mucosa

  • right ovary

  • right adrenal gland

  • right lobe of thyroid gland

  • body of uterus

  • canal of the cervix
Top expressed in
  • tail of embryo

  • genital tubercle

  • epiblast

  • ventricular zone

  • yolk sac

  • blastocyst

  • embryo

  • zygote

  • morula

  • morula
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

117246

56095

Ensembl

ENSG00000108592

ENSMUSG00000020706

UniProt

Q8IY81

Q9DBE9

RefSeq (mRNA)

NM_017647

NM_025310

RefSeq (protein)

NP_060117

NP_079586

Location (UCSC)Chr 17: 63.82 – 63.83 MbChr 11: 106.14 – 106.15 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 is an enzyme, an O-methyltransferase, that in humans is encoded by the FTSJ3 gene.

Function

The enzyme performs 2′-O-methylation of RNA using S-adenosylmethionine as methyl donor.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000108592Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000020706Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "FTSJ3 FtsJ RNA 2'-O-methyltransferase 3 [ Homo sapiens (human) ]". Retrieved 8 August 2024.

Further reading


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