Fernando Rodríguez may refer to:
- Fernando Rodríguez de Castro (1125–1185), Castilian nobleman
- Fernando Rodríguez de Castro (died 1304), Galician nobleman
- Fernando E. Rodríguez Vargas (1888–1932), dentist, scientist and army major
- Fernando Rodriguez (baseball) (born 1984), American baseball pitcher
- Freddy Rodríguez (baseball) (1924–2009), former pitcher in Major League Baseball
- Fernando Rodríguez (Argentine footballer) (born 1976), Argentine football forward
- Fernando Rodríguez (Spanish footballer) (born 1987), Spanish footballer
- Fernando Rodríguez (swimmer), Peruvian swimmer
- Fernando Rodríguez (bobsleigh) (born 1931), Argentine Olympic bobsledder
- Fernando Rodriguez Jr. (born 1969), United States District Judge
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