Francisco Gutiérrez may refer to:
- Francisco Gutierrez (1962–2005), also known as Franky G, frontman for the German Europop group Captain Jack
- Francisco Gutiérrez (sprinter) (born 1941), Colombian Olympic sprinter
- Francisco Gutiérrez Álvarez (born 1980), Spanish cyclist
- Francisco Ángel Gutiérrez Carreola (1904–1945), Mexican painter
- Francisco Gutiérrez Cabello, a Spanish Old Masters painter born circa 1616, whose works include José recibido en Heliópolis (currently held in the Museo de Bellas Artes de Sevilla)
- Francisco Gutiérrez, candidate in the Chilean parliamentary election, 2009
- Francisco Gutiérrez, sculptor, examples of whose work can be found in the Church of Santa Barbara, Madrid
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