Francisco Rodríguez may refer to:
Sports
Baseball
- Frank Rodriguez (born 1972), pitcher for the Minnesota Twins and Seattle Mariners
- Francisco Rodríguez (Venezuelan pitcher) (born 1982), relief pitcher who is nicknamed "K-Rod"
- Francisco Rodríguez (Mexican pitcher) (born 1983), Mexican League, Tigres de Quintana Roo
Boxing
- Francisco Rodríguez (boxer, born 1945) (1945–2024), Venezuelan boxer
- Francisco Rodriguez (boxer, born 1984) (1984–2009), American boxer
- Francisco Rodríguez Jr. (born 1993), Mexican boxer
Cycling
- Francisco Rodríguez (cyclist, born 1906) (1906–?), Argentine cyclist
- Francisco Rodríguez (cyclist, born 1915) (1915–1998), Mexican cyclist
- Francisco Rodríguez Maldonado (born 1960), Colombian cyclist
Football
- Francisco Javier Rodríguez (born 1981), Mexican footballer
- Francisco Rodríguez García (1934–2022), Spanish footballer
- Francisco (footballer, born 1978) (Francisco Javier Rodríguez, born 1978), Spanish footballer and manager
- Francisco Rodríguez (Swiss footballer) (born 1995), Swiss footballer
- Francisco Rodríguez (footballer, born 1993), Costa Rican footballer
Other sports
- Francisco Rodríguez (rower) (born 1953), Cuban Olympic rower
- Francisco Rodríguez (Spanish judoka) (born 1957), Spanish Olympic judoka
- Francisco Rodríguez (tennis) (born 1976), Paraguayan tennis player
- Francisco Rodríguez (Puerto Rican judoka) (born 1970), Puerto Rican Olympic judoka
- Francisco José Rodríguez [Wikidata] (born 1980), Spanish volleyball player
Other fields
- Francisco Rodríguez Adrados (1922–2020), Spanish Hellenist
- Francisco Rodríguez Pascual (1927–2007), Spanish humanist and anthropologist
- Francisco Rodríguez (President of Panama) (born 1938), in 1989
- Francisco Rodríguez Barrientos (born 1956), Costa Rican writer and sociologist
- Frankie A. Rodriguez (born 1996), American actor
- Francisco Rodríguez (economist), Venezuelan economist
See also
- Frank Rodriguez, rock organist with Question Mark & the Mysterians
- Francisco Rodrigues (disambiguation)
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