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GOLGA8A

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Protein-coding gene in the species Homo sapiens
GOLGA8A
Identifiers
AliasesGOLGA8A, GM88, golgin A8 family member A, GOLGA8B, CFAP286, FAP286
External IDsOMIM: 616180; HomoloGene: 121673; GeneCards: GOLGA8A; OMA:GOLGA8A - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)
Chromosome 15 (human)Genomic location for GOLGA8AGenomic location for GOLGA8A
Band15q14Start34,379,068 bp
End34,437,808 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sural nerve

  • right hemisphere of cerebellum

  • left lobe of thyroid gland

  • right lobe of thyroid gland

  • left ovary

  • cerebellar vermis

  • right ovary

  • Brodmann area 23

  • sperm

  • skin of hip
    n/a
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

23015

n/a

Ensembl

ENSG00000175265

n/a

UniProt

A7E2F4
A1A4C0

n/a

RefSeq (mRNA)
NM_181077
NM_001368071
NM_001368072
NM_001386893
NM_001386895

NM_015003
NM_181076

n/a

RefSeq (protein)

NP_851422
NP_001355000
NP_001355001

n/a

Location (UCSC)Chr 15: 34.38 – 34.44 Mbn/a
PubMed searchn/a
Wikidata
View/Edit Human

Golgin A8 family member A is a protein that in humans is encoded by the GOLGA8A gene.

Function

The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked, flattened membrane sacs referred to as cisternae. Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The golgins constitute a family of proteins which are localized to the Golgi. This gene encodes a golgin which structurally resembles its family member GOLGA2, suggesting that they may share a similar function. There are many similar copies of this gene on chromosome 15. Alternative splicing results in multiple transcript variants.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000175265Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Entrez Gene: Golgin A8 family member A". Retrieved 2017-05-31.

Further reading


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This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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