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Gamma-Renin

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Gamma-renin
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EC no.3.4.21.54
CAS no.85270-20-8
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Gamma-renin (EC 3.4.21.54) is an enzyme. This enzyme catalyses the following chemical reaction

Cleavage of the Leu-Leu bond in synthetic renin substrate (horse), to produce angiotensin I, but not active on natural angiotensinogen

This enzyme is present in submandibular glands of male mice.

References

  1. Poe M, Wu JK, Florance JR, Rodkey JA, Bennett CD, Hoogsteen K (February 1983). "Purification and properties of renin and gamma-renin from the mouse submaxillary gland". The Journal of Biological Chemistry. 258 (4): 2209–16. PMID 6337154.
  2. Drinkwater CC, Evans BA, Richards RI (June 1988). "Sequence and expression of mouse gamma-renin". The Journal of Biological Chemistry. 263 (18): 8565–8. PMID 3288617.

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Endopeptidases: serine proteases/serine endopeptidases (EC 3.4.21)
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