Gamma-terpinene synthase - Misplaced Pages

γ-Terpinene synthase (EC 4.2.3.114, OvTPS2, ClcTS) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase (cyclizing, γ-terpinene-forming). This enzyme catalyses the following chemical reaction

geranyl diphosphate

\rightleftharpoons

γ-terpinene + diphosphate

This enzyme is isolated from Thymus vulgaris (thyme), Citrus limon (lemon), Citrus unshiu (satsuma) and Origanum vulgare (oregano).

References

Alonso WR, Croteau R (May 1991). "Purification and characterization of the monoterpene cyclase gamma-terpinene synthase from Thymus vulgaris". Archives of Biochemistry and Biophysics. 286 (2): 511–7. doi:10.1016/0003-9861(91)90073-r. PMID 1897973.
LaFever RE, Croteau R (March 1993). "Hydride shifts in the biosynthesis of the p-menthane monoterpenes α-terpinene, γ-terpinene, and β-phellandrene". Archives of Biochemistry and Biophysics. 301 (2): 361–6. doi:10.1006/abbi.1993.1156. PMID 8460944.
Lücker J, El Tamer MK, Schwab W, Verstappen FW, van der Plas LH, Bouwmeester HJ, Verhoeven HA (July 2002). "Monoterpene biosynthesis in lemon (Citrus limon). cDNA isolation and functional analysis of four monoterpene synthases". European Journal of Biochemistry. 269 (13): 3160–71. doi:10.1046/j.1432-1033.2002.02985.x. PMID 12084056.
Suzuki Y, Sakai H, Shimada T, Omura M, Kumazawa S, Nakayama T (2004). "Characterization of gamma-terpinene synthase from Citrus unshiu (Satsuma mandarin)". BioFactors. 21 (1–4): 79–82. doi:10.1002/biof.552210115. PMID 15630174.
Crocoll C, Asbach J, Novak J, Gershenzon J, Degenhardt J (August 2010). "Terpene synthases of oregano (Origanum vulgare L.) and their roles in the pathway and regulation of terpene biosynthesis". Plant Molecular Biology. 73 (6): 587–603. doi:10.1007/s11103-010-9636-1. PMID 20419468.

External links

Gamma-terpinene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

v t e Carbon–oxygen lyases (EC 4.2) (primarily dehydratases)
4.2.1: Hydro-Lyases	Carbonic anhydrase Fumarase Aconitase Enolase Alpha Enolase 2 Enoyl-CoA hydratase/3-Hydroxyacyl ACP dehydrase Methylglutaconyl-CoA hydratase Tryptophan synthase Cystathionine beta synthase Porphobilinogen synthase 3-Isopropylmalate dehydratase Urocanase Uroporphyrinogen III synthase Nitrile hydratase
4.2.2: Acting on polysaccharides	Hyaluronate lyase Pectin lyase
4.2.3: Acting on phosphates	Threonine synthase
4.2.99: Other	Carboxymethyloxysuccinate lyase Hydroperoxide lyase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

Portal:

Biology

Category:

EC 4.2.3