Gayme may refer to:
- Gayme Magazine, a NAMBLA magazine
- Gayme Show, an American television series
- Gaymes, a nickname for the Gay Games
- LGBTQ themes in video games
- Dennice Gayme, American mechanical engineer
- Maui Gayme (born 1983), Chilean alpine skier
- Mikael Gayme (born 1979), Chilean alpine skier
See also
- R v Gayme, a 1991 Canadian Supreme Court case
- Gaymer (disambiguation)
- Gayming Magazine, a British online LGBTQ video gaming magazine
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