An absorbable gelatin sponge is a sterile hemostatic agent composed of purified porcine-derived gelatin. In regional chemotherapy, absorbable gelatin sponge may be used to embolize arteries in the region of a tumor in order to block or retard blood flow; this blockage results in a locally increased concentration of chemotherapeutic agents delivered to the tumor when chemotherapeutic agents are infused into the embolized arterial circulation upstream of the blockage. It is sometimes soaked with buprenorphine.
References
- "Definition of absorbable gelatin sponge - National Cancer Institute Drug Dictionary".
- Mishra LD, Nath SS, Gairola RL, Verma RK, Mohanty S (April 2004). "Buprenorphine-soaked absorbable gelatin sponge: an alternative method for postlaminectomy pain relief". J Neurosurg Anesthesiol. 16 (2): 115–21. doi:10.1097/00008506-200404000-00002. PMID 15021279. S2CID 23309356.
Further reading
- Shenoi PM (February 1973). "Ototoxicity of absorbable gelatin sponge". Proc. R. Soc. Med. 66 (2): 193–6. PMC 1644504. PMID 4541382.
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