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Gene Tools

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Biotechnology company
Gene Tools, LLC
HeadquartersPhilomath, Oregon
Websitewww.gene-tools.com

Gene Tools, LLC is a limited liability company located in Philomath, Oregon, United States that manufactures Morpholino antisense oligos and delivery reagents. Gene Tools was founded in 1997 and began regularly shipping custom-sequence Morpholino oligos in 2000. Current products include Morpholino oligos and Vivo-Morpholinos (for improved delivery into cells).

The manager and general partner, Jim Summerton, is a pioneer in antisense research, conceived of and was co-inventor of the Morpholino antisense oligo structural type and founded the first antisense therapeutics company, Sarepta Therapeutics Inc. (formerly AntiVirals Inc., renamed AVI BioPharma Inc., renamed Sarepta Therapeutics Inc.).

References

  1. Summerton, JE (2005). "Endo-porter: a novel reagent for safe, effective delivery of substances into cells". Ann N Y Acad Sci. 1058 (1): 62–75. Bibcode:2005NYASA1058...62S. doi:10.1196/annals.1359.012. PMID 16394126. S2CID 28590429.
  2. Morcos, PA (2001). "Achieving efficient delivery of morpholino oligos in cultured cells". Genesis. 30 (3): 94–102. doi:10.1002/gene.1039. PMID 11477682.
  3. Summerton, JE (May 1979). "Intracellular inactivation of specific nucleotide sequences: a general approach to the treatment of viral diseases and virally-mediated cancers". J. Theor. Biol. 78 (1): 77–99. Bibcode:1979JThBi..78...77S. doi:10.1016/0022-5193(79)90327-8. PMID 114718.
  4. Summerton, J; Weller D (1997). "Morpholino Antisense Oligomers: Design, Preparation and Properties" (PDF). Antisense & Nucleic Acid Drug Development. 7 (3): 187–95. doi:10.1089/oli.1.1997.7.187. PMID 9212909. S2CID 19372403. Archived from the original (PDF) on 2019-02-19.

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