George Hughes may refer to:
- George Hughes (American football) (1925–2009), NFL player
- George Hughes (cricketer) (1821–1872), English cricketer and the basis for the literary character Tom Brown
- George Hughes (engineer) (1865–1945), British locomotive engineer
- George Hughes (ice hockey) (born 1988), American professional ice hockey defenceman
- George Hughes (priest) (1603–1667), English Puritan priest and writer
- George Hughes (rugby) (1870–1947), rugby union footballer of the 1890s for England, and Barrow
- George Hughes (1889–1930), African American lynched in Sherman, Texas, see lynching of George Hughes
- George E. Hughes (1853–1937), merchant and political figure in Prince Edward Island, Canada
- George Edward Hughes (1918–1994), professor of philosophy at the Victoria University of Wellington
- George O. Hughes (born 1962), Ghanaian-born American artist
- George Wurtz Hughes (1806–1870), U.S. congressman from Maryland
- Pat Hughes (tennis) (George Patrick Hughes, 1902–1997), English tennis player
- George Hughes, Australian printer, see George Howe
Topics referred to by the same termThis disambiguation page lists articles about people with the same name. If an internal link led you here, you may wish to change the link to point directly to the intended article. Category: