Globose nucleus - Misplaced Pages

Part of the interposed nucleus, a structure in the cerebellum.

Globose nucleus
Cross-section of the cerebellum. Globose nucleus labeled at the bottom of image.
Details
Identifiers
Latin	nucleus globosus
NeuroNames	689
NeuroLex ID	birnlex_1158
TA98	A14.1.07.410
TA2	5839
FMA	72536
Anatomical terms of neuroanatomy[edit on Wikidata]

The globose nucleus is one of the deep cerebellar nuclei. It is located medial to the emboliform nucleus, and lateral to the fastigial nucleus. The globose nucleus and emboliform nucleus are known collectively as the interposed nuclei.

The globose nucleus is part of a neural circuit giving rise to descending motor tracts involved in motor control of distal musculature of the upper and lower limbs.

Anatomy

Afferents

Purkinje cells of (the paravermal cortex of) the spinocerebellum
Anterior spinocerebellar tract (via restiform body of inferior cerebellar peduncle)

Efferents

Contralateral (magnocellular division of) red nucleus (via the superior cerebellar peduncle). This is the major major efferent projection of the globose nucleus. The red nucleus in turn gives rise to the rubrospinal tract.
Ipsilateral ventral lateral nucleus of thalamus. The VL nucleus in turn projects to the primary motor cortex and premotor cortex (which then give rise to the lateral corticospinal tract).

Cell biology

This nucleus contains primarily large and small multipolar neurons.

References

^ Patestas, Maria A.; Gartner, Leslie P. (2016). A Textbook of Neuroanatomy (2nd ed.). Hoboken, New Jersey: Wiley-Blackwell. pp. 291–292. ISBN 978-1-118-67746-9.

This article incorporates text in the public domain from page 796 of the 20th edition of Gray's Anatomy (1918)