| gluconolactonase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Gluconolactonase homodimer, Xanthomonas campestris | |||||||||
| Identifiers | |||||||||
| EC no. | 3.1.1.17 | ||||||||
| CAS no. | 9012-73-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme gluconolactonase (EC 3.1.1.17) catalyzes the reaction
- D-glucono-1,5-lactone + H2O D-gluconate
D-gluconateThis enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is D-glucono-1,5-lactone lactonohydrolase. Other names in common use include lactonase, aldonolactonase, glucono-δ-lactonase, and gulonolactonase. This enzyme participates in three metabolic pathways: pentose phosphate pathway, ascorbate and aldarate metabolism, and caprolactam degradation.
References
- BRODIE AF, LIPMANN F (1955). "Identification of a gluconolactonase". J. Biol. Chem. 212 (2): 677–85. PMID 14353869.
- Bublitz C; Lehninger AL (1961). "The role of aldonolactonase in the conversion of L-gulonate to L-ascorbate". Biochim. Biophys. Acta. 47 (2): 288–297. doi:10.1016/0006-3002(61)90289-X.
- Suzuki K, Kawada M, Shimazono N. "Soluble lactonase. Identity of lactonase I and aldonolactonase with gluconolactonase". J. Biochem. 49: 448–449.
| Enzymes | |
|---|---|
| Activity | |
| Regulation | |
| Classification | |
| Kinetics | |
| Types |
|
This EC 3.1 enzyme-related article is a stub. You can help Misplaced Pages by expanding it. |