Misplaced Pages

Glycine betaine aldehyde

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
Glycine betaine aldehyde
Names
IUPAC name N,N,N-Trimethylglycinium
Systematic IUPAC name N,N,N-Trimethyl-2-oxoethan-1-aminium
Other names Betaine aldehyde
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChemSpider
KEGG
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1/C5H12NO/c1-6(2,3)4-5-7/h5H,4H2,1-3H3/q+1Key: SXKNCCSPZDCRFD-UHFFFAOYAL
SMILES
  • O=CC(C)(C)C
Properties
Chemical formula C5H12NO
Molar mass 102.157 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Glycine betaine aldehyde, often simply called betaine aldehyde, is an intermediate in the metabolism of glycine, serine and threonine. The human aldehyde dehydrogenase (EC 1.2.1.3) stimulates the transformation of betaine aldehyde to glycine betaine. Betaine aldehyde is a substrate for choline dehydrogenase (mitochondrial).

Chemical structure

Glycine betaine aldehyde is a short chain aldehyde and quaternary ammonium compound. It can be considered a derivative of the amino acid glycine. Its chemical formula is C5H12NO.

Biological function

Glycine betaine aldehyde is a component of glycine, serine and threonine metabolism. It also serves as an osmolyte.

It can be found in cytoplasm and mitochondria within the kidney, neurons, and stratum corneum.

References

  1. Betaine aldehyde Archived 2007-11-24 at the Wayback Machine, Biological Magnetic Resonance Data Bank
  2. Yilmaz JL, Bülow L. (December 2002). "Enhanced stress tolerance in Escherichia coli and Nicotiana tabacum expressing a betaine aldehyde dehydrogenase/choline dehydrogenase fusion protein". Biotechnol. Prog. 18 (6): 1176–82. doi:10.1021/bp020057k. PMID 12467448. S2CID 8054758.
  3. , Human Metabolome Database
Categories: