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Granulibacter bethesdensis is a Gram-negative, aerobic coccobacillus to rod-shaped, non-motile, catalase-positive and oxidase-negative bacteria first described in 2006 by Dr. Steve Holland's team, which included Dr. David E. Greenberg and Dr. Patrick R. Murray at the National Institutes of Health in Bethesda, Maryland.

Clinical Significance

Granulibacter bethesdensis was identified in a series of patients with chronic granulomatous disease (CGD). In a later study, nearly half of patients with CGD tested and a quarter of healthy volunteers showed some immunoreactivity to Granulibacter bethesdensis, suggesting infections with this organism occur more often than it is isolated.

References

1. ^ Greenberg, DE; Porcella SF; Stock F; Wong A; Conville PS; Murray PR; Holland SM; Zelazny AM (Nov 2006). "Granulibacter bethesdensis gen. nov., sp. nov., a distinctive pathogenic acetic acid bacterium in the family Acetobacteraceae". Int J Syst Evol Microbiol. Pt 11. 56 (11): 2609–16. doi:10.1099/ijs.0.64412-0. PMID 17082400.
2. Greenberg, DE; Shoffner AR; Marshall-Batty KR; Arora K; Zhao M; Martin R; Ding L; Hammer CH; Shaw PA; Kuhns DB; Malech HL; Gallin JI; Zarember KA; Holland SM (Sep 2012). "Serologic reactivity to the emerging pathogen Granulibacter bethesdensis". J Infect Dis. 206 (6): 943–51. doi:10.1093/infdis/jis431. PMC 3501152. PMID 22782953.

External links

• LPSN
• "Granulibacter bethesdensis". The Encyclopedia of Life.
• Type strain of Granulibacter bethesdensis at BacDive - the Bacterial Diversity Metadatabase

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