Gretchen is a female given name.
Gretchen may also refer to:
- Gretchen (band), a female-fronted alternative rock band
- Gretchen (film), a 2006 film
- Gretchen (play), an 1879 play by W. S. Gilbert based on the Faust legend
- Gretchen (singer) (born 1959), Brazilian singer and dancer
- Hurricane Gretchen, three tropical cyclones in the Eastern Pacific Ocean
- USS Gretchen, the name of more than one United States Navy ship
- Gretchen Goes to Nebraska, a 1990 album by King's X, often called Gretchen
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