Gustavo Santos may refer to:
- Gustavo dos Santos (born 1991), Brazilian sprinter
- Gustavo Santos (footballer) (born 2002), Brazilian football forward
- Gustavo Santos (politician), Argentine politician
- Gustavo Almeida dos Santos (born 1996), Brazilian football forward
- Gustavo Sant'Ana Santos (born 1995), Brazilian football defender
- Gustavo Santos Costa (born 1996), Brazilian football forward
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