HLE or hle may refer to:
Transportation
- Heiligerlee railway stop (Station code Hle), the Netherlands
- Hillington East railway station (Station code HLE), Scotland
- Saint Helena Airport (IATA airport code), Saint Helena
Science and technology
- Hardware Lock Elision, part of Intel's Transactional Synchronization Extensions
- High-level emulation, is an emulator for the Nintendo 64
Other uses
- Happy life expectancy, life expectancy multiplied by a happiness index
- Harold Lloyd Entertainment
- HLE (singer), stage name of South African gospel singer Hlengiwe Ntombela
- Hlersu language (ISO 639-3 code), spoken in China
- Holy Land Experience, a theme park in Orlando, Florida, US
- Hong Kong Higher Level Examination, a standardized examination from 1979 to 1992
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