Haematin (also known as hematin, ferriheme, hematosin, hydroxyhemin, oxyheme, phenodin, or oxyhemochromogen) is a dark bluish or brownish pigment containing iron in the ferric state, obtained by the oxidation of haem.
Haematin inhibits the synthesis of porphyrin (by repressing ALAS1 synthesis), and stimulates the synthesis of globin. For this reason, it is used in the treatment of porphyrias.
It is a component of cytochromes and peroxidases. Haematin derived synthetically from hemin is used as a reagent.
References
- "haematin. (n.d.) Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. (2003). Retrieved December 17 2015".
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(help) - ^ Rodwell, Victor W. (2018). Harper's Illustrated Biochemistry (31st ed.). McGraw-Hill Education. p. 311. ISBN 978-1-25-983794-4.
- "haematin. (n.d.) Dorland's Medical Dictionary for Health Consumers. (2007). Retrieved December 17 2015".
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