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Hemoglobin J is an abnormal hemoglobin, an alpha globin gene variant and present in various geographic locations. It was first reported in a black American family in 1956, and later reported from Indonesia, India, and other parts of the world. Hemoglobin J reported from Meerut India shows the mutation of 120th alanine to glutamic acid on alpha chain. Hemoglobin J was also reported from Chhattisgarh, Central India as revealed by Lingojwar and coworkers in 2016.
References
- Thorup, O (1956). "Hemoglobin j". Science. 123 (3203): 889–890. Bibcode:1956Sci...123..889T. doi:10.1126/science.123.3203.889. PMID 13324107.
- Blackwell, R (May 10, 1974). "Hemoglobin J Meerut: alpha120 Ala leads to Glu". Biochim Biophys Acta. 351 (1): 7–12. doi:10.1016/0005-2795(74)90060-9. PMID 4600474.
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