Henry David Erskine may refer to:
- Henry David Erskine, 10th Earl of Buchan (1710–1767), Scottish peer
- Henry David Erskine, 12th Earl of Buchan (1783–1857), Scottish peer
- Henry David Erskine (priest) (died 1859), Scottish clergyman
- Sir (Henry) David Erskine of Cardross (1838–1921), Scottish military officer and Serjeant-at-Arms of the House of Commons
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