Hisamitsu may refer to:
- Hisamitsu Pharmaceutical, a Japanese pharmaceutical company
- Hisamitsu Springs, a Japanese women's volleyball team based in Kobe city, Hyogo
People with the given name
- Hisamitsu Kawahara (川原 永光, born 1978), Japanese futsal player
- Shimazu Hisamitsu (島津 久光, 1817–1887), Japanese samurai and daimyō
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