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Historical annual reformulations of the influenza vaccine

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Influenza (flu)
H1N1 virus
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Since 1999, the World Health Organization (WHO) has issued annual recommendations for influenza vaccine formulations. One reformulation of the influenza vaccine is for the Northern Hemisphere, and the other is for the Southern Hemisphere. Both recommendations are trivalent, i.e. featuring three strains.

Since the 2012–2013 season, the WHO recommendations have also included the formulation of an annual quadrivalent vaccine, featuring an additional strain of Influenza B virus, B/Yamagata.

Due to the widespread use of non-pharmaceutical interventions at the beginning of the COVID-19 pandemic, the B/Yamagata influenza lineage has not been isolated since March 2020, and may have been eradicated. Starting with the 2024 Southern Hemisphere influenza season, the WHO and other regulatory bodies have removed this strain from influenza vaccine recommendations.

Northern Hemisphere recommended strains

The following is a list of WHO recommended strains for the Northern Hemisphere influenza season. Starting in the 2012–2013 season, the recommendation shifted to include the composition of a quadrivalent influenza vaccine (QIV) that contains both influenza B lineages, alongside a trivalent influenza vaccine (TIV) containing one influenza B lineage.

NH winter season Influenza A H1N1 Influenza A H3N2 Influenza B Victoria Influenza B Yamagata
1998–1999 A/Beijing/262/95 (H1N1)-like virus A/Sydney/5/97 (H3N2)-like virus N/A B/Beijing/184/93-like virus
1999–2000 A/Beijing/262/95 (H1N1)-like virus A/Sydney/5/97 (H3N2)-like virus B/Shangdong/7/97-like virus B/Beijing/184/93-like virus
2000–2001 A/New Caledonia/20/99 (H1N1)-like virus A/Moscow/10/99 (H3N2)-like virus N/A B/Beijing/184/93-like virus
2001–2002 A/New Caledonia/20/99 (H1N1)-like virus A/Moscow/10/99 (H3N2)-like virus N/A B/Sichuan/379/99-like virus
2002–2003 A/New Caledonia/20/99 (H1N1)-like virus A/Moscow/10/99 (H3N2)-like virus B/Hong Kong/330/2001-like virus N/A
2003–2004 A/New Caledonia/20/99 (H1N1)-like virus A/Moscow/10/99 (H3N2)-like virus B/Hong Kong/330/2001-like virus N/A
2004–2005 A/New Caledonia/20/99 (H1N1)-like virus A/Fujian/411/2002 (H3N2)-like virus N/A B/Shanghai/361/2002-like virus
2005–2006 A/New Caledonia/20/99 (H1N1)-like virus A/California/7/2004 (H3N2)-like virus N/A B/Shanghai/361/2002-like virus
2006–2007 A/New Caledonia/20/99 (H1N1)-like virus A/Wisconsin/67/2005 (H3N2)-like virus B/Malaysia/2506/2004-like virus N/A
2007–2008 A/Solomon Islands/3/2006 (H1N1)-like virus A/Wisconsin/67/2005 (H3N2)-like virus B/Malaysia/2506/2004-like virus N/A
2008–2009 A/Brisbane/59/2007 (H1N1)-like virus A/Brisbane/10/2007 (H3N2)-like virus N/A B/Florida/4/2006-like virus
2009–2010 A/Brisbane/59/2007 (H1N1)-like virus A/Brisbane/10/2007 (H3N2)-like virus B/Brisbane/60/2008-like virus N/A
2010–2011 A/California/7/2009 (H1N1)-like virus A/Perth/16/2009 (H3N2)-like virus B/Brisbane/60/2008-like virus N/A
2011–2012 A/California/7/2009 (H1N1)-like virus A/Perth/16/2009 (H3N2)-like virus B/Brisbane/60/2008-like virus N/A
2012–2013 A/California/7/2009 (H1N1)pdm09-like virus A/Victoria/361/2011 (H3N2)-like virus B/Brisbane/60/2008-like virus B/Wisconsin/1/2010-like virus
2013–2014 A/California/7/2009 (H1N1)pdm09-like virus A(H3N2) virus antigenically like the cell-propagated prototype virus A/Victoria/361/2011 B/Brisbane/60/2008-like virus B/Massachusetts/2/2012-like virus
2014–2015 A/California/7/2009 (H1N1)pdm09-like virus A/Texas/50/2012 (H3N2)-like virus B/Brisbane/60/2008-like virus B/Massachusetts/2/2012-like virus
2015–2016 A/California/7/2009 (H1N1)pdm09-like virus A/Switzerland/9715293/2013 (H3N2)-like virus B/Brisbane/60/2008-like virus B/Phuket/3073/2013-like virus
2016–2017 A/California/7/2009 (H1N1)pdm09-like virus A/Hong Kong/4801/2014 (H3N2)-like virus B/Brisbane/60/2008-like virus B/Phuket/3073/2013-like virus
2017–2018 A/Michigan/45/2015 (H1N1)pdm09-like virus A/Hong Kong/4801/2014 (H3N2)-like virus B/Brisbane/60/2008-like virus B/Phuket/3073/2013-like virus
2018–2019 A/Michigan/45/2015 (H1N1)pdm09-like virus A/Singapore/INFIMH-16-0019/2016 (H3N2)-like virus B/Colorado/06/2017-like virus (B/Victoria/2/87 lineage) B/Phuket/3073/2013-like virus (B/Yamagata/16/88 lineage)
2019–2020 A/Brisbane/02/2018 (H1N1)pdm09-like virus A/Kansas/14/2017 (H3N2)-like virus B/Colorado/06/2017-like virus (B/Victoria/2/87 lineage) B/Phuket/3073/2013-like virus (B/Yamagata/16/88 lineage)
2020–2021 egg-based vaccines A/Guangdong-Maonan/SWL1536/2019 (H1N1)pdm09-like virus A/Hong Kong/2671/2019 (H3N2)-like virus B/Washington/02/2019 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2020–2021 cell- or recombinant-based vaccines A/Hawaii/70/2019 (H1N1)pdm09-like virus A/Hong Kong/45/2019 (H3N2)-like virus B/Washington/02/2019 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2021–2022 egg-based vaccines A/Victoria/2570/2019 (H1N1)pdm09-like virus A/Cambodia/e0826360/2020 (H3N2)-like virus B/Washington/02/2019 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2021–2022 cell- or recombinant-based vaccines A/Wisconsin/588/2019 (H1N1)pdm09-like virus A/Cambodia/e0826360/2020 (H3N2)-like virus B/Washington/02/2019 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2022–2023 egg-based vaccines A/Victoria/2570/2019 (H1N1)pdm09-like virus A/Darwin/9/2021 (H3N2)-like virus B/Austria/1359417/2021 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2022–2023 cell- or recombinant-based vaccines A/Wisconsin/588/2019 (H1N1)pdm09-like virus A/Darwin/6/2021 (H3N2)-like virus B/Austria/1359417/2021 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2023–2024 egg-based vaccines A/Victoria/4897/2022 (H1N1)pdm09-like virus A/Darwin/9/2021 (H3N2)-like virus B/Austria/1359417/2021 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2023–2024 cell- or recombinant-based vaccines A/Wisconsin/67/2022 (H1N1)pdm09-like virus A/Darwin/6/2021 (H3N2)-like virus B/Austria/1359417/2021 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2024–2025 egg-based vaccines A/Victoria/4897/2022 (H1N1)pdm09-like virus A/Thailand/8/2022 (H3N2)-like virus B/Austria/1359417/2021 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2024–2025 cell- or recombinant-based vaccines A/Wisconsin/67/2022 (H1N1)pdm09-like virus A/Massachusetts/18/2022 (H3N2)-like virus B/Austria/1359417/2021 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus

Southern Hemisphere recommended strains

The following is a list of WHO recommended strains for the Southern Hemisphere influenza season.

SH winter season Influenza A H1N1 Influenza A H3N2 Influenza B Victoria Influenza B Yamagata
1999 A/Beijing/262/95 (H1N1)-like virus A/Sydney/5/97 (H3N2)-like virus N/A B/Beijing/184/93-like virus
2000 A/New Caledonia/20/99 (H1N1)-like virus A/Moscow/10/99 (H3N2)-like virus B/Shangdong/7/97-like virus B/Beijing/184/93-like virus
2001 A/New Caledonia/20/99 (H1N1)-like virus A/Moscow/10/99 (H3N2)-like virus N/A B/Sichuan/379/99-like virus
2002 A/New Caledonia/20/99 (H1N1)-like virus A/Moscow/10/99 (H3N2)-like virus N/A B/Sichuan/379/99-like virus
2003 A/New Caledonia/20/99 (H1N1)-like virus A/Moscow/10/99 (H3N2)-like virus B/Hong Kong/330/2001-like virus N/A
2004 A/New Caledonia/20/99 (H1N1)-like virus A/Fujian/411/2002 (H3N2)-like virus B/Hong Kong/330/2001-like virus N/A
2005 A/New Caledonia/20/99 (H1N1)-like virus A/Wellington/1/2004 (H3N2)-like virus N/A B/Shanghai/361/2002-like virus
2006 A/New Caledonia/20/99 (H1N1)-like virus A/California/7/2004 (H3N2)-like virus B/Malaysia/2506/2004-like virus N/A
2007 A/New Caledonia/20/99 (H1N1)-like virus A/Wisconsin/67/2005 (H3N2)-like virus B/Malaysia/2506/2004-like virus N/A
2008 A/Solomon Islands/3/2006 (H1N1)-like virus A/Brisbane/10/2007 (H3N2)-like virus N/A B/Florida/4/2006-like virus
2009 A/Brisbane/59/2007 (H1N1)-like virus A/Brisbane/10/2007 (H3N2)-like virus N/A B/Florida/4/2006-like virus
2010 A/California/7/2009 (H1N1)-like virus A/Perth/16/2009 (H3N2)-like virus B/Brisbane/60/2008-like virus N/A
2011 A/California/7/2009 (H1N1)-like virus A/Perth/16/2009 (H3N2)-like virus B/Brisbane/60/2008-like virus N/A
2012 A/California/7/2009 (H1N1)pdm09-like virus A/Perth/16/2009 (H3N2)-like virus B/Brisbane/60/2008-like virus N/A
2013 A/California/7/2009 (H1N1)pdm09-like virus A/Victoria/361/2011 (H3N2)-like virus B/Brisbane/60/2008-like virus B/Wisconsin/1/2010-like virus
2014 A/California/7/2009 (H1N1)pdm09-like virus A/Texas/50/2012 (H3N2)-like virus B/Brisbane/60/2008-like virus B/Massachusetts/2/2012-like virus
2015 A/California/7/2009 (H1N1)pdm09-like virus A/Switzerland/9715293/2013 (H3N2)-like virus B/Brisbane/60/2008-like virus B/Phuket/3073/2013-like virus
2016 A/California/7/2009 (H1N1)pdm09-like virus A/Hong Kong/4801/2014 (H3N2)-like virus B/Brisbane/60/2008-like virus B/Phuket/3073/2013-like virus
2017 A/Michigan/45/2015 (H1N1)pdm09-like virus A/Hong Kong/4801/2014 (H3N2)-like virus B/Brisbane/60/2008-like virus B/Phuket/3073/2013-like virus
2018 A/Michigan/45/2015 (H1N1)pdm09-like virus A/Singapore/INFIMH-16-0019/2016 (H3N2)-like virus B/Brisbane/60/2008-like virus B/Phuket/3073/2013-like virus
2019 A/Michigan/45/2015 (H1N1)pdm09-like virus A/Switzerland/8060/2017 (H3N2)-like virus B/Colorado/06/2017-like virus (B/Victoria/2/87 lineage) B/Phuket/3073/2013-like virus (B/Yamagata/16/88 lineage)
2020 A/Brisbane/02/2018 (H1N1)pdm09-like virus A/South Australia/34/2019 (H3N2)-like virus B/Washington/02/2019-like (B/Victoria lineage) virus B/Phuket/3073/2013-like (B/Yamagata lineage) virus
2021 egg-based vaccines A/Victoria/2570/2019 (H1N1)pdm09-like virus A/Hong Kong/2671/2019 (H3N2)-like virus B/Washington/02/2019 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2021 cell- or recombinant-based vaccines A/Wisconsin/588/2019 (H1N1)pdm09-like virus A/Hong Kong/45/2019 (H3N2)-like virus B/Washington/02/2019 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2022 egg-based vaccines A/Victoria/2570/2019 (H1N1)pdm09-like virus A/Darwin/9/2021 (H3N2)-like virus B/Austria/1359417/2021 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2022 cell- or recombinant-based vaccines A/Wisconsin/588/2019 (H1N1)pdm09-like virus A/Darwin/6/2021 (H3N2)-like virus B/Austria/1359417/2021 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2023 egg-based vaccines A/Sydney/5/2021 (H1N1)pdm09-like virus A/Darwin/9/2021 (H3N2)-like virus B/Austria/1359417/2021 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2023 cell- or recombinant-based vaccines A/Sydney/5/2021 (H1N1)pdm09-like virus A/Darwin/6/2021 (H3N2)-like virus B/Austria/1359417/2021 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2024 egg-based vaccines A/Victoria/4897/2022 (H1N1)pdm09-like virus A/Thailand/8/2022 (H3N2)-like virus B/Austria/1359417/2021 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus
2024 cell- or recombinant-based vaccines A/Wisconsin/67/2022 (H1N1)pdm09-like virus A/Massachusetts/18/2022 (H3N2)-like virus B/Austria/1359417/2021 (B/Victoria lineage)-like virus B/Phuket/3073/2013 (B/Yamagata lineage)-like virus

See also

Notes

  1. ^ The recommendation was for either the B/Victoria or the B/Yamagata strain.
  2. ^ (H1N1)pdm09 is newer nomenclature for the 2009 pandemic H1N1 virus, not a different strain.
  3. It is recommended that A/Texas/50/2012 is used as the A(H3N2) vaccine component because of antigenic changes in earlier A/Victoria/361/2011-like vaccine viruses (such as IVR-165) resulting from adaptation to propagation in eggs.
  4. ^ A/Texas/50/2012 is an A(H3N2) virus that following adaptation to growth in eggs has maintained antigenic properties similar to the majority of recently circulating cell-propagated A(H3N2) viruses including A/Victoria/361/2011.
  5. ^ The WHO, the FDA, and the EMA advise that the B/Yamagata lineage antigen should be excluded from influenza vaccines as it is no longer warranted.

References

  1. Anker M, Schaaf D, World Health Organization (2000). WHO report on global surveillance of epidemic-prone infectious diseases (PDF) (Report). World Health Organization (WHO). hdl:10665/66485. WHO/CDS/CSR/ISR/2000.1. Archived (PDF) from the original on 31 October 2022.
  2. ^ Rudenko L, Kiseleva I, Krutikova E, Stepanova E, Rekstin A, Donina S, et al. (3 December 2018). "Rationale for vaccination with trivalent or quadrivalent live attenuated influenza vaccines: Protective vaccine efficacy in the ferret model". PLOS ONE. 13 (12) e0208028: e0208028. Bibcode:2018PLoSO..1308028R. doi:10.1371/journal.pone.0208028. PMC 6277076. PMID 30507951.
  3. Schnirring L (29 September 2023). "WHO advisers recommend switch back to trivalent flu vaccines". Center for Infectious Disease Research and Policy. Archived from the original on 18 December 2023. Retrieved 23 January 2024.
  4. ^ "Use of Trivalent Influenza Vaccines for the 2024-2025 U.S. flu season". U.S. Food and Drug Administration (FDA). 5 March 2024. Archived from the original on 7 March 2024. Retrieved 7 March 2024. Public Domain This article incorporates text from this source, which is in the public domain.
  5. "EU recommendations for 2024/2025 seasonal flu vaccine composition". European Medicines Agency (EMA). 26 March 2024. Archived from the original on 28 March 2024. Retrieved 28 March 2024.
  6. "Recommendations for Influenza Vaccine Composition Northern hemisphere November 1998-April 1999". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 14 June 2012.
  7. "Recommendations for Influenza Vaccine Composition Northern hemisphere: November 1999 to April 2000". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 14 June 2012.
  8. "Recommendations for Influenza Vaccine Composition Northern hemisphere: 2000-2001". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 14 June 2012.
  9. "Recommendations for Influenza Vaccine Composition Northern hemisphere: 2001-2002". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 14 June 2012.
  10. "Recommendations for Influenza Vaccine Composition Northern hemisphere: 2002-2003". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 14 June 2012.
  11. "Recommendations for Influenza Vaccine Composition Northern hemisphere: 2003-2004". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 14 June 2012.
  12. "Recommendations for Influenza Vaccine Composition Northern hemisphere: 2004-2005". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 14 June 2012.
  13. "Recommendations for Influenza Vaccine Composition Northern hemisphere: 2005-2006". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 14 June 2012.
  14. "Recommendations for Influenza Vaccine Composition Northern hemisphere: 2006-2007". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 14 June 2012.
  15. "Recommendations for Influenza Vaccine Composition Northern hemisphere: 2007-2008". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 14 June 2012.
  16. "Recommendations for Influenza Vaccine Composition Northern hemisphere: 2008-2009". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 14 June 2012.
  17. "Recommendations for Influenza Vaccine Composition Northern hemisphere: 2009-2010". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 14 June 2012.
  18. "Recommended viruses for influenza vaccines for use in the 2010-2011 northern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 28 October 2013. Retrieved 14 June 2012.
  19. "Recommended composition of influenza virus vaccines for use in the 2011-2012 northern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 9 October 2011. Retrieved 14 June 2012.
  20. "Recommended composition of influenza virus vaccines for use in the 2012-2013 northern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 27 February 2012. Retrieved 14 June 2012.
  21. ^ "Standardization of terminology of the pandemic A(H1N1) 2009 virus" (PDF). World Health Organization (WHO). Archived (PDF) from the original on 8 March 2022. Retrieved 14 June 2012.
  22. "Recommended composition of influenza virus vaccines for use in the 2013-2014 northern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 1 March 2013. Retrieved 22 February 2013.
  23. "Recommended composition of influenza virus vaccines for use in the 2014-2015 northern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 25 February 2014. Retrieved 20 February 2014.
  24. "Recommended composition of influenza virus vaccines for use in the 2015-2016 northern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 6 March 2015. Retrieved 2 March 2015.
  25. "Recommended composition of influenza virus vaccines for use in the 2016-2017 northern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 4 March 2016. Retrieved 19 May 2016.
  26. World Health Organization (March 2016). "Recommended composition of influenza virus vaccines for use in the 2016–2017 northern hemisphere influenza season". Weekly Epidemiological Record. 91 (10): 121–32. hdl:10665/254302. PMID 26971356.
  27. "Recommended composition of influenza virus vaccines for use in the 2017-2018 northern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 7 March 2017. Retrieved 16 March 2017.
  28. World Health Organization (March 2017). "Recommended composition of influenza virus vaccines for use in the 2017–2018 northern hemisphere influenza season". Weekly Epidemiological Record. 92 (11): 117–28. hdl:10665/254758. PMID 28303704.
  29. ^ "WHO switches H1N1 in Southern Hemisphere flu vaccine". University of Minnesota - Center for Infectious Disease Research and Policy (CIDRAP). 29 September 2016. Archived from the original on 12 September 2017. Retrieved 12 September 2017. A/Michigan/45/2015 replaces the longstanding A/California/7/2009 and is recommended to improve protection against two subclades that have emerged over the past season.
  30. "Recommended composition of influenza virus vaccines for use in the 2018-2019 northern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 26 February 2018. Retrieved 22 February 2018.
  31. World Health Organization (March 2018). "Recommended composition of influenza virus vaccines for use in the 2018–2019 northern hemisphere influenza season". Weekly Epidemiological Record. 93 (12): 133–41. hdl:10665/272270. PMID 29569429.
  32. "Recommended composition of influenza virus vaccines for use in the 2019-2020 northern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 29 March 2022. Retrieved 22 March 2019.
  33. World Health Organization (March 2019). "Recommended composition of influenza virus vaccines for use in the 2019–2020 northern hemisphere influenza season". Weekly Epidemiological Record. 94 (12): 141–50. hdl:10665/311441.
  34. World Health Organization (March 2019). "Addendum to the Recommended composition of influenza virus vaccines for use in the 2019–2020 northern hemisphere influenza season". Weekly Epidemiological Record. 94 (13): 166–8. hdl:10665/311555.
  35. ^ "Recommended composition of influenza virus vaccines for use in the 2020-2021 northern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 12 March 2020. Retrieved 28 February 2020.
  36. ^ "Recommended composition of influenza virus vaccines for use in the 2021-2022 northern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 26 February 2021. Retrieved 26 February 2021.
  37. ^ "Recommended composition of influenza virus vaccines for use in the 2022-2023 northern hemisphere influenza season". World Health Organization (WHO). 25 February 2022. Archived from the original on 29 March 2022. Retrieved 29 March 2022.
  38. ^ "Recommended composition of influenza virus vaccines for use in the 2023-2024 northern hemisphere influenza season". World Health Organization (WHO). 24 February 2023. Archived from the original on 8 March 2023. Retrieved 17 March 2023.
  39. ^ "Influenza Vaccine for the 2023-2024 Season". U.S. Food and Drug Administration (FDA). 3 March 2022. Archived from the original on 5 July 2023. Retrieved 4 July 2023.
  40. ^ "Recommended composition of influenza virus vaccines for use in the 2024-2025 northern hemisphere influenza season". World Health Organization (WHO). 23 February 2024. Archived from the original on 23 February 2024. Retrieved 23 February 2024.
  41. "Recommendations for Influenza Vaccine Composition Southern hemisphere 1999". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 22 June 2012.
  42. "Recommendations for Influenza Vaccine Composition Southern hemisphere: May–October 2000". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 22 June 2012.
  43. "Recommendations for Influenza Vaccine Composition Southern hemisphere: May–October 2001". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 22 June 2012.
  44. "Recommendations for Influenza Vaccine Composition Southern hemisphere: 2002". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 22 June 2012.
  45. "Recommendations for Influenza Vaccine Composition Southern hemisphere: 2003". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 22 June 2012.
  46. "Recommendations for Influenza Vaccine Composition Southern hemisphere: 2004". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 22 June 2012.
  47. "Recommendations for Influenza Vaccine Composition Southern hemisphere: 2005". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 22 June 2012.
  48. "Recommendations for Influenza Vaccine Composition Southern hemisphere: 2006". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 22 June 2012.
  49. "Recommendations for Influenza Vaccine Composition Southern hemisphere: 2007". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 22 June 2012.
  50. "Recommendations for Influenza Vaccine Composition Southern hemisphere: 2008". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 22 June 2012.
  51. "Recommendations for Influenza Vaccine Composition Southern hemisphere: 2009". World Health Organization (WHO). Archived from the original on 29 April 2013. Retrieved 22 June 2012.
  52. "Recommendations for Influenza Vaccine Composition Southern hemisphere: 2010". World Health Organization (WHO). Archived from the original on 14 November 2011. Retrieved 22 June 2012.
  53. "Recommended composition of influenza virus vaccines for use in the 2011 southern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 14 November 2011. Retrieved 22 June 2012.
  54. "Recommended composition of influenza virus vaccines for use in the 2012 southern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 3 October 2011. Retrieved 22 June 2012.
  55. "Recommended composition of influenza virus vaccines for use in the 2013 southern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 29 March 2022. Retrieved 18 October 2012.
  56. "Recommended composition of influenza virus vaccines for use in the 2014 southern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 26 September 2013. Retrieved 30 September 2013.
  57. "Recommended composition of influenza virus vaccines for use in the 2015 southern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 29 September 2014. Retrieved 2 October 2014.
  58. "Recommended composition of influenza virus vaccines for use in the 2016 southern hemisphere influenza season". World Health Organization (WHO). Archived from the original on 27 September 2015. Retrieved 30 November 2015.
  59. "Recommended composition of influenza virus vaccines for use in the 2017 southern hemisphere influenza season". World Health Organization (WHO). 29 September 2016. Archived from the original on 2 October 2016. Retrieved 22 October 2016.
  60. World Health Organization (October 2016). "Recommended composition of influenza virus vaccines for use in the 2017 southern hemisphere influenza season". Weekly Epidemiological Record. 91 (41): 469–84. hdl:10665/250513. PMID 27758094.
  61. "Recommended composition of influenza virus vaccines for use in the 2018 southern hemisphere influenza season". World Health Organization (WHO). 28 September 2017. Archived from the original on 2 October 2017. Retrieved 28 September 2017.
  62. World Health Organization (October 2017). "Recommended composition of influenza virus vaccines for use in the 2018 southern hemisphere influenza season". Weekly Epidemiological Record. 92 (42): 625–33. hdl:10665/259276. PMID 29052409.
  63. "Recommended composition of influenza virus vaccines for use in the 2019 southern hemisphere influenza season". World Health Organization (WHO). 27 September 2018. Archived from the original on 1 October 2018. Retrieved 27 September 2018.
  64. World Health Organization (October 2018). "Recommended composition of influenza virus vaccines for use in the 2019 southern hemisphere influenza season". Weekly Epidemiological Record. 93 (42): 553–62. hdl:10665/275476.
  65. "Recommended composition of influenza virus vaccines for use in the 2020 southern hemisphere influenza season". World Health Organization (WHO). 27 September 2019. Archived from the original on 20 October 2019. Retrieved 3 October 2019.
  66. World Health Organization (October 2019). "Recommended composition of influenza virus vaccines for use in the 2020 southern hemisphere influenza season". Weekly Epidemiological Record. 94 (42): 473–84. hdl:10665/329391.
  67. ^ "Recommended composition of influenza virus vaccines for use in the 2021 southern hemisphere influenza season". World Health Organization (WHO). 25 September 2020. Archived from the original on 3 October 2020. Retrieved 16 October 2020.
  68. ^ "Recommended composition of influenza virus vaccines for use in the 2022 southern hemisphere influenza season". World Health Organization (WHO). 24 September 2021. Archived from the original on 29 March 2022. Retrieved 29 March 2022.
  69. ^ "Recommended composition of influenza virus vaccines for use in the 2023 southern hemisphere influenza season". World Health Organization (WHO). 23 September 2022. Archived from the original on 28 September 2022. Retrieved 28 September 2022.
  70. ^ "Recommended composition of influenza virus vaccines for use in the 2024 southern hemisphere influenza season". World Health Organization (WHO). 29 September 2023. Archived from the original on 3 December 2023. Retrieved 23 January 2024.
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