Homestake may refer to:
- Homestake Creek, in Eagle County, Colorado
- Homestake experiment, an experiment headed by astrophysicists Raymond Davis, Jr. and John N. Bahcall in the late 1960s
- Homestake Pass, a mountain pass in the Rocky Mountains of Montana in the United States
- Homestake Mining Company, one of the largest gold mining businesses in the United States from the 19th century through the beginning of the 21st
- Homestake Mine (disambiguation), the name for several mines in the United States
- Homestake Reservoir, in Colorado, U.S.
- Homestake, a formation on Mars analyzed by Opportunity rover, which was concluded to be formed of gypsum
This disambiguation page lists articles associated with the title Homestake.If an internal link led you here, you may wish to change the link to point directly to the intended article. Category: