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Igf like family member 3

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Protein-coding gene in the species Homo sapiens
IGFL3
Identifiers
AliasesIGFL3, UNQ483, IGF like family member 3
External IDsOMIM: 610546; MGI: 2685426; HomoloGene: 74410; GeneCards: IGFL3; OMA:IGFL3 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)
Chromosome 19 (human)Genomic location for IGFL3Genomic location for IGFL3
Band19q13.32Start46,120,067 bp
End46,124,688 bp
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)
Chromosome 7 (mouse)Genomic location for IGFL3Genomic location for IGFL3
Band7|7 A2Start17,910,419 bp
End17,915,787 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • skin of leg

  • skin of abdomen

  • testicle

  • gonad

  • corpus callosum

  • sural nerve

  • smooth muscle tissue

  • mucosa of transverse colon

  • duodenum

  • right lung
Top expressed in
  • zone of skin

  • lens

  • lip
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

388555

232925

Ensembl

ENSG00000188624

ENSMUSG00000066756

UniProt

Q6UXB1

Q6B9Z0

RefSeq (mRNA)

NM_207393

NM_001003393

RefSeq (protein)

NP_997276

NP_001003393

Location (UCSC)Chr 19: 46.12 – 46.12 MbChr 7: 17.91 – 17.92 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

IGF like family member 3 is a protein that in humans is encoded by the IGFL3 gene.

Function

IGFL3 belongs to the insulin-like growth factor (IGF; see MIM 147440) family of signaling molecules that play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth (Emtage et al., 2006 ).

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000188624Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000066756Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: IGF like family member 3". Retrieved 2016-03-20.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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