Insúa is a surname. Notable people with the surname include:
- Emanuel Insúa (born 1991), Argentine footballer
- Emiliano Insúa (born 1989), Argentine footballer
- Federico Insúa (born 1980), Argentine former footballer
- Pablo Insúa (born 1993), Spanish footballer
- Rubén Insúa (born 1961), Argentine football manager
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