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(Redirected from Insecticidal) Pesticide used against insects For other uses, see Insecticide (disambiguation). For the Nirvana compilation album, see Incesticide.
FLIT manual spray pump from 1928
Farmer spraying a cashewnut tree in Tanzania

Insecticides are pesticides used to kill insects. They include ovicides and larvicides used against insect eggs and larvae, respectively. The major use of insecticides is in agriculture, but they are also used in home and garden settings, industrial buildings, for vector control, and control of insect parasites of animals and humans.

Acaricides, which kill mites and ticks, are not strictly insecticides, but are usually classified together with insecticides. Some insecticides (including common bug sprays) are effective against other non-insect arthropods as well, such as scorpions, spiders, etc. Insecticides are distinct from insect repellents, which repel but do not kill.

Sales

In 2016 insecticides were estimated to account for 18% of worldwide pesticide sales. Worldwide sales of insecticides in 2018 were estimated as $ 18.4 billion, of which 25% were neonicotinoids, 17% were pyrethroids, 13% were diamides, and the rest were many other classes which sold for less than 10% each of the market.

Synthetic insecticides

Insecticides are most usefully categorised according to their modes of action. The insecticide resistance action committee (IRAC) list s 30 modes of action plus unknowns. There can be several chemical classes of insecticide with the same mode or action. IRAC lists 56 chemical classed plus unknowns. Further Information: List of insecticides.

The mode of action describes how the insecticide kills or inactivates a pest. It provides another way of classifying insecticides.

Development

Main article: pesticide § Development of new pesticides

Insecticides with systemic activity against sucking pests, which are safe to pollinators, are sought after, particularly in view of the partial bans on neonicotinoids. Revised 2023 guidance by registration authorities describes the bee testing that is required for new insecticides to be approved for commercial use.

Systemicity and Translocation

Insecticides may be systemic or non-systemic (contact insecticides). Systemic insecticides penetrate into the plant and move (translocate) inside the plant. Translocation may be upward in the xylem, or downward in the phloem or both. Systemicity is a prerequisite for the pesticide to be used as a seed-treatment. Contact insecticides (non-systemic insecticides) remain on the leaf surface and act through direct contact with the insect.

Insects feed from various compartments in the plant. Most of the major pests are either chewing insects or sucking insects. Chewing insects, such as caterpillars, eat whole pieces of leaf. Sucking insects use feeding tubes to feed from phloem (e.g. aphids, leafhoppers, scales and whiteflies), or to suck cell contents (e.g. thrips and mites). An insecticide is more effective if it is in the compartment the insect feeds from. The physicochemical properties of the insecticide determine how it is distributed throughout the plant.

Organochlorides

The best known organochloride, DDT, was created by Swiss scientist Paul Müller. For this discovery, he was awarded the 1948 Nobel Prize for Physiology or Medicine. DDT was introduced in 1944. It functions by opening sodium channels in the insect's nerve cells. The contemporaneous rise of the chemical industry facilitated large-scale production of chlorinated hydrocarbons including various cyclodiene and hexachlorocyclohexane compounds. Although commonly used in the past, many older chemicals have been removed from the market due to their health and environmental effects (e.g. DDT, chlordane, and toxaphene).

Organophosphates

Organophosphates are another large class of contact insecticides. These also target the insect's nervous system. Organophosphates interfere with the enzymes acetylcholinesterase and other cholinesterases, causing an increase in synaptic acetylcholine and overstimulation of the parasympathetic nervous system. and killing or disabling the insect. Organophosphate insecticides and chemical warfare nerve agents (such as sarin, tabun, soman, and VX) have the same mechanism of action. Organophosphates have a cumulative toxic effect to wildlife, so multiple exposures to the chemicals amplifies the toxicity. In the US, organophosphate use declined with the rise of substitutes. Many of these insecticides, first developed in the mid 20th century, are very poisonous. Many organophosphates do not persist in the environment.

Carbamates

Carbamate insecticides have similar mechanisms to organophosphates, but have a much shorter duration of action and are somewhat less toxic.

Pyrethroids

Pyrethroid insecticides mimic the insecticidal activity of the natural compound pyrethrin, the biopesticide found in Pyrethrum (Now Chrysanthemum and Tanacetum) species. They have been modified to increase their stability in the environment. These compounds are nonpersistent sodium channel modulators and are less toxic than organophosphates and carbamates. Compounds in this group are often applied against household pests. Some synthetic pyrethroids are toxic to the nervous system.

Neonicotinoids

Neonicotinoids are a class of neuro-active insecticides chemically similar to nicotine.(with much lower acute mammalian toxicity and greater field persistence). These chemicals are acetylcholine receptor agonists. They are broad-spectrum systemic insecticides, with rapid action (minutes-hours). They are applied as sprays, drenches, seed and soil treatments. Treated insects exhibit leg tremors, rapid wing motion, stylet withdrawal (aphids), disoriented movement, paralysis and death.Imidacloprid, of the neonicotinoid family, is the most widely used insecticide in the world. In the late 1990s neonicotinoids came under increasing scrutiny over their environmental impact and were linked in a range of studies to adverse ecological effects, including honey-bee colony collapse disorder (CCD) and loss of birds due to a reduction in insect populations. In 2013, the European Union and a few non EU countries restricted the use of certain neonicotinoids. and its potential to increase the susceptibility of rice to planthopper attacks.

Phenylpyrazoles

Phenylpyrazole insecticides, such as fipronil are a class of synthetic insecticides that operate by interfering with GABA receptors.

Butenolides

Butenolide pesticides are a novel group of chemicals, similar to neonicotinoids in their mode of action, that have so far only one representative: flupyradifurone. They are acetylcholine receptor agonists, like neonicotinoids, but with a different pharmacophore. They are broad-spectrum systemic insecticides, applied as sprays, drenches, seed and soil treatments. Although the classic risk assessment considered this insecticide group (and flupyradifurone specifically) safe for bees, novel research has raised concern on their lethal and sublethal effects, alone or in combination with other chemicals or environmental factors.

Diamides

Diamides selectively activate insect ryanodine receptors (RyR), which are large calcium release channels present in cardiac and skeletal muscle, leading to the loss of calcium crucial for biological processes. This causes insects to act lethargic, stop feeding, and eventually die. The first insecticide from this class to be registered was flubendiamide.

Insect growth regulators

Insect growth regulator (IGR) is a term coined to include insect hormone mimics and an earlier class of chemicals, the benzoylphenyl ureas, which inhibit chitin (exoskeleton) biosynthesis in insects Diflubenzuron is a member of the latter class, used primarily to control caterpillars that are pests. Of these, methoprene is most widely used. It has no observable acute toxicity in rats and is approved by World Health Organization (WHO) for use in drinking water cisterns to combat malaria. Most of its uses are to combat insects where the adult is the pest, including mosquitoes, several fly species, and fleas. Two very similar products, hydroprene and kinoprene, are used for controlling species such as cockroaches and white flies. Methoprene was registered with the EPA in 1975. Virtually no reports of resistance have been filed. A more recent type of IGR is the ecdysone agonist tebufenozide (MIMIC), which is used in forestry and other applications for control of caterpillars, which are far more sensitive to its hormonal effects than other insect orders.

Biological pesticides

Main article: Biopesticide

Definition

The EU defines biopesticides as "a form of pesticide based on micro-organisms or natural products". The US EPA defines biopesticides as “certain types of pesticides derived from such natural materials as animals, plants, bacteria, and certain minerals”. Microorganisms that control pests may also be categorised as biological pest control agents together with larger organisms such as parasitic insects, entomopathic nematodes etc. Natural products may also be categorised as chemical insecticides.

The US EPA describes three types of biopesticide. Biochemical pesticides (meaning bio-derived chemicals), which are naturally occurring substances that control pests by non-toxic mechanisms. Microbial pesticides consisting of a microorganism (e.g., a bacterium, fungus, virus or protozoan) as the active ingredient. Plant-Incorporated-Protectants (PIPs) are pesticidal substances that plants produce from genetic material that has been added to the plant (thus producing transgenic crops).

Market

The global bio-insecticide market was estimated to be less than 10% of the total insecticide market. The bio-insecticde market is dominated by microbials. The bio-insecticide market is growing more that 10% yearly, which is a higher growth than the total insecticide market, mainly due to the increase in organic farming and IPM, and also due to benevolent government policies.

Biopesticides are regarded by the US and European authorities as posing fewer risks of environmental and mammalian toxicity. Biopesticides are more than 10 x (often 100 x) cheaper and 3 x faster to register than synthetic pesticides.

Advantages and disadvantages

There is a wide variety of biological insecticides with differing attributes, but in general the following has been described.

They are easier, faster and cheaper to register, usually with lower mammalian toxicity. They are more specific, and thus preserve beneficial insects and biodiversity in general. This makes them compatible with IPM regimes. They degrade rapidly cause less impact on the environment. They have a shorter withholding period.

The spectrum of control is narrow. They are less effective and prone to adverse ambient conditions. They degrade rapidly and are thus less persistant. They are slower to act. They are more expensive, have a shorter shelf-life, and are more difficult to source. They require mor specialised knowledge to use.

Plant Extracts

Most or all plants produce chemical insecticides to stop insects eating them. Extracts and purified chemicals from thousands of plants have been shown to be insecticidal, however only a few are used in agriculture. In the USA 13 are registered for use, in the EU 6. In Korea, where it is easier to register botanical pesticides, 38 are used. Most used are neem oil, chenopodium, pyrethrins, and azadirachtin. Many botanical insecticides used in past decades (e.g. rotenone, nicotine, ryanodine) have been banned because of their toxicity.

Genetically modified crops

The first transgenic crop, which incorporated an insecticidal PIP, contained a gene for the CRY toxin from Bacillus thuringiensis (B.t.) and was introduced in 1997. For the next ca 25 years the only insecticidal agents used in GMOs were the CRY and VIP toxins from various strains of B.t, which control a wide number of insect types. These are widely used with > 100 million hectares planted with B.t. modified crops in 2019. Since 2020 several novel agents have been engineered into plants and approved.  ipd072Aa from Pseudomonas chlororaphis, ipd079Ea from Ophioglossum pendulum, and mpp75Aa1.1 from Brevibacillus laterosporus code for protein toxins. The trait dvsnf7 is an RNAi agent consisting of a double-stranded RNA transcript containing a 240 bp fragment of the WCR Snf7 gene of the western corn rootworm (Diabrotica virgifera virgifera).

RNA interference

RNA interference (RNAi) uses segments of RNA to fatally silence crucial insect genes. In 2024 two uses of RNAi have been registered by the authorities for use:Genetic modification of a crop to introduce a gene coding for an RNAi fragment, and spraying double stranded RNA fragments onto a field. Monsanto introduced the trait DvSnf7 which expresses a double-stranded RNA transcript containing a 240 bp fragment of the WCR Snf7 gene of the Western Corn Rootworm. GreenLight Biosciences introduced Ledprona, a formulation of double stranded RNA as a spray for potato fields. It targets the essential gene for proteasome subunit beta type-5 (PSMB5) in the Colorado potato beetle.

Spider toxins

Spider venoms contain many, often hundreds, of insecticidally active toxins. Many are proteins that attack the nervous system of the insect. Vestaron introduced for agricultural use a spray formulation of GS-omega/kappa-Hxtx-Hv1a (HXTX), derived from the venom of the Australian blue mountain funnel web spider (Hadronyche versuta).

Entomopathic bacteria

Entomopathic bacteria can be mass-produced. The most widely used is Bacillus thuringiensis (B.t.), used since decades. There are several strains used with different applications against lepidoptera, coleoptera and diptera. Also used are Lysinibacillus sphaericus, Burkholderia spp, and Wolbachia pipientis. Avermectins and spinosyns are bacterial metabolites, mass-produced by fermentation and used as insecticides. The toxins from B.t. have been incorporated into plants through genetic engineering.

Entomopathic fungi

Entomopathic fungi have been used since 1965 for agricultural use. Hundreds of strains are now in use. They often kill a broad range of insect species. Most strains are from Beauveria, Metarhizium, Cordyceps and Akanthomyces species.

Entomopathic viruses

Of the many types of entomopathic viruses, only baculaviruses are used commercially, and are each specific for their target insect. They have to be grown on insects, so their production is labour-intensive.

Environmental toxicity

Effects on nontarget species

Some insecticides kill or harm other creatures in addition to those they are intended to kill. For example, birds may be poisoned when they eat food that was recently sprayed with insecticides or when they mistake an insecticide granule on the ground for food and eat it. Sprayed insecticide may drift from the area to which it is applied and into wildlife areas, especially when it is sprayed aerially.

Persistence in the environment and accumulation in the food chain

DDT was the first organic insecticide. It was introduced during WW2, and was widely used. One use was vector control and it was sprayed on open water. It degrades slowly in the environment, and it is lipophilic (fat soluble). It became the first global pollutant, and the first pollutant to accumulate and magnify in the food chain. During the 1950s and 1960s these very undesirable side effects were recognized, and after some often contentious discussion, DDT was banned in many countries in the 1960s and 1970s. Finally in 2001 DDT and all other persistent insecticides were banned via the Stockholm Convention. Since many decades the authorities require new insecticides to degrade in the environment and not to bioaccumulate.

Runoff and percolation

Solid bait and liquid insecticides, especially if improperly applied in a location, get moved by water flow. Often, this happens through nonpoint sources where runoff carries insecticides in to larger bodies of water. As snow melts and rainfall moves over and through the ground, the water picks applied insecticides and deposits them in to larger bodies of water, rivers, wetlands, underground sources of previously potable water, and percolates in to watersheds. This runoff and percolation of insecticides can effect the quality of water sources, harming the natural ecology and thus, indirectly effect human populations through biomagnification and bioaccumulation.

Insect decline

Both number of insects and number of insect species have declined dramatically and continuously over past decades, causing much concern. Many causes are proposed to contribute to this decline, the most agreed upon are loss of habitat, intensification of farming practices, and insecticide usage. Domestic bees were declining some years ago but population and number of colonies have now risen both in the USA and worldwide. Wild species of bees are still declining.

Bird decline

Besides the effects of direct consumption of insecticides, populations of insectivorous birds decline due to the collapse of their prey populations. Spraying of especially wheat and corn in Europe is believed to have caused an 80 per cent decline in flying insects, which in turn has reduced local bird populations by one to two thirds.

Alternatives

Instead of using chemical insecticides to avoid crop damage caused by insects, there are many alternative options available now that can protect farmers from major economic losses. Some of them are:

  1. Breeding crops resistant, or at least less susceptible, to pest attacks.
  2. Releasing predators, parasitoids, or pathogens to control pest populations as a form of biological control.
  3. Chemical control like releasing pheromones into the field to confuse the insects into not being able to find mates and reproduce.
  4. Integrated Pest Management: using multiple techniques in tandem to achieve optimal results.
  5. Push-pull technique: intercropping with a "push" crop that repels the pest, and planting a "pull" crop on the boundary that attracts and traps it.

Examples

Source:

Organochlorides

See also: Category:Organochloride insecticides

Organophosphates

See also: Category:Organophosphate insecticides

Carbamates

Pyrethroids

Neonicotinoids

Ryanoids

Insect growth regulators

Derived from plants or microbes

Biologicals

Inorganic/mineral derived insecticides

See also

References

  1. IUPAC (2006). "Glossary of Terms Relating to Pesticides" (PDF). IUPAC. p. 2123. Retrieved January 28, 2014.
  2. ^ Delso, N. Simon (2015). "Systemic insecticides (neonicotinoids and fipronil): trends, uses, mode of action and metabolites". Environmental Science and Pollution Research. 22 (1): 5–34. Bibcode:2015ESPR...22....5S. doi:10.1007/s11356-014-3470-y. PMC 4284386. PMID 25233913.
  3. Sparks, Thomas C (2024). "Insecticide mixtures—uses, benefits and considerations". Pest Management Science. doi:10.1002/ps.7980. PMID 38356314 – via Wiley.
  4. Sparks, Thomas (August 2022). "Innovation in insecticide discovery: Approaches to the discovery of new classes of insecticides". Pest Management Science. 78 (8): 3226–3247. doi:10.1002/ps.6942. PMID 35452182. S2CID 248322585.
  5. Sparks, Thomas (May 2023). "Insecticide discovery–"Chance favors the prepared mind"". Pesticide Biochemistry and Physiology. 192: 105412. Bibcode:2023PBioP.19205412S. doi:10.1016/j.pestbp.2023.105412. PMID 37105622. S2CID 257790593.
  6. Umetsu, Noriharu (May 2020). "Development of novel pesticides in the 21st century". Journal of Pesticide Science. 45 (2): 54–74. doi:10.1584/jpestics.D20-201. PMC 7581488. PMID 33132734.
  7. "Bees and pesticides: updated guidance for assessing risks". European Food Safety Authority. 11 May 2023. Retrieved 26 Nov 2023.
  8. Adriaanse, Pauline (11 May 2023). "Revised guidance on the risk assessment of plant protection products on bees (Apis mellifera, Bombus spp. and solitary bees)". EFSA Journal. 21 (5): 7989. doi:10.2903/j.efsa.2023.7989. PMC 10173852. PMID 37179655.
  9. "How We Assess Risks to Pollinators". United States Environmental Protection Agency. 28 June 2023.
  10. "Managing Pesticide Risk to Insect Pollinators; Laws, Policies and Guidance". Organisation for Economic Cooperation and Development. Retrieved 28 Nov 2023.
  11. ^ Zhang, Y; Lorsbach, BA; Castetter, S; Lambert, WT; Kister, J; Wang, N (2018). "Physicochemical property guidelines for modern agrochemicals". Pest Management Science. 74 (9): 1979-1991. doi:10.1002/ps.5037. PMID 29667318. S2CID 4937939.
  12. ^ Hofstetter, S (2018). "How To Design for a Tailored Subcellular Distribution of Systemic Agrochemicals in Plant Tissues" (PDF). J. Agric. Food Chem. 66 (33): 8687–8697. Bibcode:2018JAFC...66.8687H. doi:10.1021/acs.jafc.8b02221. PMID 30024749. S2CID 261974999.
  13. Cloyd, Raymond A. (10 May 2022). "Insect and Mite Pests Feeding Behaviors and Plant Damage". Greenhouse Product News. Retrieved 3 November 2024.
  14. Karl Grandin, ed. (1948). "Paul Müller Biography". Les Prix Nobel. The Nobel Foundation. Retrieved 2008-07-24.
  15. Vijverberg; et al. (1982). "Similar mode of action of pyrethroids and DDT on sodium channel gating in myelinated nerves". Nature. 295 (5850): 601–603. Bibcode:1982Natur.295..601V. doi:10.1038/295601a0. PMID 6276777. S2CID 4259608.
  16. "Public Health Statement for DDT, DDE, and DDD" (PDF). atsdr.cdc.gov. ATSDR. Sep 2002. Archived (PDF) from the original on 2008-09-23. Retrieved Dec 9, 2018.
  17. "Medical Management Guidelines (MMGs): Chlordane". atsdr.cdc.gov. ATSDR. Apr 18, 2012. Retrieved Dec 9, 2018.
  18. Colović MB, Krstić DZ, Lazarević-Pašti TD, Bondžić AM, Vasić VM (May 2013). "Acetylcholinesterase inhibitors: pharmacology and toxicology". Current Neuropharmacology. 11 (3): 315–35. doi:10.2174/1570159X11311030006. PMC 3648782. PMID 24179466.
  19. ^ Palmer, W.E.; Bromley, P.T.; Brandenburg, R.L. "Integrated Pest Management | NC State Extension". North Carolina State Extension. Retrieved 14 October 2007.
  20. "Infographic: Pesticide Planet". Science. 341 (6147): 730–731. 2013. Bibcode:2013Sci...341..730.. doi:10.1126/science.341.6147.730. PMID 23950524.
  21. "Toxicological Profile for Toxaphene" (PDF). ntp.niehs.nih.gov. ATSDR. Aug 1996. p. 5. Retrieved Dec 9, 2018.
  22. Class, Thomas J.; Kintrup, J. (1991). "Pyrethroids as household insecticides: analysis, indoor exposure and persistence". Fresenius' Journal of Analytical Chemistry. 340 (7): 446–453. doi:10.1007/BF00322420. S2CID 95713100.
  23. Soderlund D (2010). "Chapter 77 – Toxicology and Mode of Action of Pyrethroid Insecticides". In Kreiger R (ed.). Hayes' Handbook of Pesticide Toxicology (3rd ed.). Academic Press. pp. 1665–1686. ISBN 978-0-12-374367-1. OCLC 918401061.
  24. Fishel, Frederick M. (9 March 2016). "Pesticide Toxicity Profile: Neonicotinoid Pesticides". Archived from the original on 28 April 2007. Retrieved 11 March 2012.
  25. Yamamoto I (1999). "Nicotine to Nicotinoids: 1962 to 1997". In Yamamoto I, Casida J (eds.). Nicotinoid Insecticides and the Nicotinic Acetylcholine Receptor. Tokyo: Springer-Verlag. pp. 3–27. ISBN 978-4-431-70213-9. OCLC 468555571.
  26. Cressey, D (2013). "Europe debates risk to bees". Nature. 496 (7446): 408. Bibcode:2013Natur.496..408C. doi:10.1038/496408a. ISSN 1476-4687. PMID 23619669.
  27. Gill, RJ; Ramos-Rodriguez, O; Raine, NE (2012). "Combined pesticide exposure severely affects individual- and colony-level traits in bees". Nature. 491 (7422): 105–108. Bibcode:2012Natur.491..105G. doi:10.1038/nature11585. ISSN 1476-4687. PMC 3495159. PMID 23086150.
  28. Dicks L (2013). "Bees, lies and evidence-based policy". Nature. 494 (7437): 283. Bibcode:2013Natur.494..283D. doi:10.1038/494283a. ISSN 1476-4687. PMID 23426287.
  29. Stoddart, C (2012). "The buzz about pesticides". Nature. doi:10.1038/nature.2012.11626. ISSN 1476-4687. S2CID 208530336.
  30. Osborne JL (2012). "Ecology: Bumblebees and pesticides". Nature. 491 (7422): 43–45. Bibcode:2012Natur.491...43O. doi:10.1038/nature11637. ISSN 1476-4687. PMID 23086148. S2CID 532877.
  31. Cressey, D (2013). "Reports spark row over bee-bothering insecticides". Nature. doi:10.1038/nature.2013.12234. ISSN 1476-4687. S2CID 88428354.
  32. "Bees & Pesticides: Commission goes ahead with plan to better protect bees". 30 May 2013. Archived from the original on 21 June 2013.
  33. "Insecticides taking toll on honeybees". Archived from the original on March 18, 2012.
  34. Yao, Cheng; Shi, Zhao-Peng; Jiang, Li-Ben; Ge, Lin-Quan; Wu, Jin-Cai; Jahn, Gary C. (20 January 2012). "Possible connection between imidacloprid-induced changes in rice gene transcription profiles and susceptibility to the brown plant hopper Nilaparvata lugens Stål (Hemiptera: Delphacidae)". Pesticide Biochemistry and Physiology. 102 (3): 213–219. Bibcode:2012PBioP.102..213C. doi:10.1016/j.pestbp.2012.01.003. ISSN 0048-3575. PMC 3334832. PMID 22544984. Archived from the original on 24 May 2013.
  35. "Fipronil- A Phenylpyrazole Pesticides | Solvent Toxicity- Diethylene Glycol". u.osu.edu.
  36. Nauen, Ralf; Jeschke, Peter; Velten, Robert; Beck, Michael E; Ebbinghaus-Kintscher, Ulrich; Thielert, Wolfgang; Wölfel, Katharina; Haas, Matthias; Kunz, Klaus; Raupach, Georg (June 2015). "Flupyradifurone: a brief profile of a new butenolide insecticide". Pest Management Science. 71 (6): 850–862. doi:10.1002/ps.3932. PMC 4657471. PMID 25351824.
  37. "Pesticide Marketed as Safe for Bees Harms Them in Study". The Scientist Magazine®. Retrieved 2020-08-01.
  38. Tosi, S.; Nieh, J. C. (2019-04-10). "Lethal and sublethal synergistic effects of a new systemic pesticide, flupyradifurone (Sivanto®), on honeybees". Proceedings of the Royal Society B: Biological Sciences. 286 (1900): 20190433. doi:10.1098/rspb.2019.0433. PMC 6501679. PMID 30966981.
  39. Tong, Linda; Nieh, James C.; Tosi, Simone (2019-12-01). "Combined nutritional stress and a new systemic pesticide (flupyradifurone, Sivanto®) reduce bee survival, food consumption, flight success, and thermoregulation". Chemosphere. 237: 124408. Bibcode:2019Chmsp.23724408T. doi:10.1016/j.chemosphere.2019.124408. ISSN 0045-6535. PMID 31356997.
  40. Nauen, Ralf; Steinbach, Denise (27 August 2016). "Resistance to Diamide Insecticides in Lepidopteran Pests". In Horowitz, A. Rami; Ishaaya, Isaac (eds.). Advances in Insect Control and Resistance Management. Cham: Springer (published 26 August 2016). pp. 219–240. doi:10.1007/978-3-319-31800-4_12. ISBN 978-3-319-31800-4.{{cite book}}: CS1 maint: date and year (link)
  41. ^ Du, Shaoqing; Hu, Xueping (February 15, 2023). "Comprehensive Overview of Diamide Derivatives Acting as Ryanodine Receptor Activators". Journal of Agricultural and Food Chemistry. 71 (8): 3620–3638. Bibcode:2023JAFC...71.3620D. doi:10.1021/acs.jafc.2c08414. PMID 36791236.{{cite journal}}: CS1 maint: date and year (link)
  42. Krysan, James; Dunley, John. "Insect Growth Regulators". Archived from the original on 17 May 2018. Retrieved 20 April 2017.
  43. "Encouraging innovation in biopesticide development" (PDF) (News alert). European Commission DG ENV. 18 December 2008. Issue 134. Archived from the original (PDF) on 15 May 2012. Retrieved 20 April 2012.
  44. ^ "What are Biopesticides?". United States Environmental Protection Agency. 18 October 2023. Retrieved 9 Oct 2024.
  45. ^ Marrone, Pamela G. (2024). "Status of the biopesticide market and prospects for new bioherbicides". Pest Management Science. 80 (1): 81–86. doi:10.1002/ps.7403. PMID 36765405.
  46. ^ Glare, T.R.; Jurat-Fuentes, J.-L.; O’Callaghan, M (2017). "Chapter 4 - Basic and Applied Research: Entomopathogenic Bacteria". In Lacey, Lawrence A. (ed.). Microbial Control of Insect and Mite Pests. Academic Press. pp. 47–67. doi:10.1016/B978-0-12-803527-6.00004-4. ISBN 9780128035276.
  47. Mihăiță, Daraban Gabriel; Hlihor, Raluca-Maria; Suteu, Daniela (2023). "Pesticides vs. Biopesticides: From Pest Management to Toxicity and Impacts on the Environment and Human Health". Toxics. 11 (12): 983. doi:10.3390/toxics11120983. PMC 10748064. PMID 38133384.
  48. "Advantages and Disadvantages of Biological Control". INTERNATIONAL SCHOOL OF AGRI MANAGEMENT S.L. 5 September 2024. Retrieved 12 October 2024.
  49. ^ Isman, Murray B. (2020). "Botanical Insecticides in the Twenty-First Century—Fulfilling Their Promise?". Annual Review of Entomology. 65: 233–249. doi:10.1146/annurev-ento-011019-025010. PMID 31594414.
  50. ^ Barry, Jennifer K.; Simmons, Carl R.; Nelson, Mark E (2023). "Chapter Five - Beyond Bacillus thuringiensis: New insecticidal proteins with potential applications in agriculture". In Jurat-Fuentes, Juan Luis (ed.). Advances in Insect Physiology Volume 65. Elsevier. pp. 185–233. doi:10.1016/bs.aiip.2023.09.004. ISBN 9780323954662.
  51. ^ "International Service for the Acquisition of Agri-biotech Applications (ISAAA)". International Service for the Acquisition of Agri-biotech Applications (ISAAA). 2024. Retrieved 9 October 2024.
  52. ^ Vélez, Ana M.; Narva, Ken; Darlington, Molly; Mishra, Swati; Hellmann, Christoph; Rodrigues, Thais B.; Duman-Scheel, Molly; Palli, Subba Reddy; Jurat-Fuentes, Juan Luis (2023). "Chapter One - Insecticidal proteins and RNAi in the control of insects". In Jurat-Fuentes, Juan Luis (ed.). Advances in Insect Physiology. Vol. 65. Academic Press. pp. 1–54. doi:10.1016/bs.aiip.2023.09.007. ISBN 9780323954662.
  53. Zhu, Kun Yan; Palli, Subba Reddy (2020-01-07). "Mechanisms, Applications, and Challenges of Insect RNA Interference". Annual Review of Entomology. 65 (1). Annual Reviews: 293–311. doi:10.1146/annurev-ento-011019-025224. ISSN 0066-4170. PMC 9939233. PMID 31610134. S2CID 204702574.
  54. ^ King, Glenn F (2019). "Tying pest insects in knots: the deployment of spider-venom-derived knottins as bioinsecticides". Pest Manag. Sci. 75 (9): 2437–2445. doi:10.1002/ps.5452. PMID 31025461.
  55. Jiang, Y.; Wang, J. (2023). "The Registration Situation and Use of Mycopesticides in the World". J. Fungi. 9 (9): 940. doi:10.3390/jof9090940. PMC 10532538. PMID 37755048.
  56. Nikhil Raj, M.; Samal, Ipsita; Paschapur, Amit; Subbanna, A.R.N.S. (2022). "Chapter 3 - Entomopathogenic viruses and their potential role in sustainable pest management". In Bahadur, Harikesh (ed.). New and Future Developments in Microbial Biotechnology and Bioengineering. Elsevier. pp. 47–72. doi:10.1016/B978-0-323-85579-2.00015-0. ISBN 9780323855792.
  57. Castro, Peter; Huber, Michael E. (2010). Marine Biology (8th ed.). New York: McGraw-Hill Companies Inc. ISBN 978-0-07-352416-0. OCLC 488863548.
  58. Pesticide Usage in the United States: History, Benefits, Risks, and Trends; Bulletin 1121, November 2000, K.S. Delaplane, Cooperative Extension Service, The University of Georgia College of Agricultural and Environmental Sciences "Archived copy" (PDF). Archived from the original (PDF) on 2010-06-13. Retrieved 2012-11-10.{{cite web}}: CS1 maint: archived copy as title (link)
  59. Quinn, Amie L. (2007). The impacts of agricultural chemicals and temperature on the physiological stress response in fish (MSc Thesis). Lethbridge: University of Lethbridge.
  60. "Stockholm Convention on Persistent Organic Pollutants (POPs)". Stockholm Convention on Persistent Organic Pollutants. 2024. Retrieved 6 October 2024.
  61. "Ridding The World of Pops: A Guide to the Stockholm Convention on Persistent Organic Pollutants" (PDF). United Nations Environment Programme. April 2005. Archived from the original (PDF) on 15 March 2017. Retrieved 5 February 2017.
  62. "Pesticide Registration". United States Environmental Protection Agency. 19 August 2024. Retrieved 16 October 2024.
  63. Environmental Protection Agency (2005). "Protecting Water Quality from Agricultural Runoff" (PDF). EPA.gov. Retrieved 2019-11-19.
  64. Wagner, David L. (14 October 2019). "Insect Declines in the Anthropocene". Annu. Rev. Entomol. 65: 457–480. doi:10.1146/annurev-ento-011019-025151. PMID 31610138.
  65. Sánchez-Bayo, Francisco; Wyckhuys, Kris A.G. (2019). "Worldwide decline of the entomofauna: A review of its drivers". Biol. Conserv. 232 (April): 8–27. Bibcode:2019BCons.232....8S. doi:10.1016/j.biocon.2019.01.020 – via Elsevier Science Direct.
  66. van der Sluijs, Jeroen. P. (October 2020). "Insect decline, an emerging global environmental risk". Curr. Opin. Environ. Sustain. 46 (October): 39–42. Bibcode:2020COES...46...39V. doi:10.1016/j.cosust.2020.08.012. hdl:11250/2764289 – via Elsevier Science Direct.
  67. Oldroyd, B.P. (2007). "What's Killing American Honey Bees?". PLOS Biology. 5 (6): e168. doi:10.1371/journal.pbio.0050168. PMC 1892840. PMID 17564497.
  68. "Table 21. Colonies of Honey Bees - Inventory and Honey Sales: 2022 and 2017" (PDF). USDA National Agricultural Statistics Service Census of Agriculture. Retrieved 12 November 2024.
  69. "Bee colonies: Worldwide population on the rise". Federal Statistical Office of Germany. 2 March 2023. Retrieved 12 November 2023.
  70. "Catastrophic collapse in farmland bird populations across France". BirdGuides. 21 March 2018. Retrieved 27 March 2018.
  71. Aidley, David (Summer 1976). "Alternatives to insecticides". Science Progress. 63 (250): 293–303. JSTOR 43420363. PMID 1064167.
  72. Russell, GE (1978). Plant Breeding for Pest and Disease Resistance. Elsevier. ISBN 978-0-408-10613-9.
  73. "Biological Control and Natural Enemies of Invertebrates Management Guidelines--UC IPM". ipm.ucanr.edu. Retrieved 2018-12-12.
  74. "Mating Disruption". jenny.tfrec.wsu.edu. Archived from the original on 2018-06-12. Retrieved 2018-12-12.
  75. "Defining IPM | New York State Integrated Pest Management". nysipm.cornell.edu. Retrieved 2018-12-12.
  76. Cook, Samantha M.; Khan, Zeyaur R.; Pickett, John A. (2007). "The use of push-pull strategies in integrated pest management". Annual Review of Entomology. 52: 375–400. doi:10.1146/annurev.ento.52.110405.091407. ISSN 0066-4170. PMID 16968206.
  77. "Interactive MoA Classification". Insecticide Resistance Action Committee. 2020-09-16. Retrieved 2021-04-01.
  78. ^ "Cinnamon Oil Kills Mosquitoes". www.sciencedaily.com. Retrieved 5 August 2008.
  79. "Cornelia Dick-Pfaff: Wohlriechender Mückentod, 19.07.2004". www.wissenschaft.de. Archived from the original on 2006-03-24. Retrieved 2008-08-04.
  80. Comprehensive natural products chemistry (1st ed.). Amsterdam: Elsevier. 1999. p. 306. ISBN 978-0-08-091283-7.
  81. Bentley, Ronald (2008). "A fresh look at natural tropolonoids". Nat. Prod. Rep. 25 (1): 118–138. doi:10.1039/B711474E. PMID 18250899.
  82. "R.E.D. FACTS: Limonene" (PDF). EPA – United States Environmental Protection Agency.
  83. "BIOPESTICIDES REGISTRATION ACTION DOCUMENT" (PDF). U.S. Environmental Protection Agency.
  84. US EPA, OCSPP (10 August 2020). "Nootkatone Now Registered by EPA". US EPA.
  85. "Oregano Oil Works As Well As Synthetic Insecticides To Tackle Common Beetle Pest". www.sciencedaily.com. Retrieved 23 May 2008.
  86. "Almond farmers seek healthy bees". BBC News. 2006-03-08. Retrieved 2010-01-05.
  87. ^ "Bacteria". Biological Control. Cornell University. Archived from the original on 2011-09-09.

Further reading

  • McWilliams James E (2008). "'The Horizon Opened Up Very Greatly': Leland O. Howard and the Transition to Chemical Insecticides in the United States, 1894–1927". Agricultural History. 82 (4): 468–95. doi:10.3098/ah.2008.82.4.468. PMID 19266680.

External links


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