Avacincaptad pegol - Misplaced Pages

(Redirected from Izervay) Medication

Pharmaceutical compound

Avacincaptad pegol
Clinical data
Trade names	Izervay
Other names	Zimura
License data	US DailyMed: Avacincaptad pegol
Routes of administration	Intravitreal
Drug class	Complement inhibitor
ATC code	None
Legal status
Legal status	US: ℞-only
Identifiers
CAS Number	1613641-69-2
DrugBank	DB15165
UNII	TT0V5JLG5B
KEGG	D11748
Chemical and physical data
Formula	C₃₉₅H₄₅₃F₂₁N₁₄₂Na₃₉O₂₆₂P₃₉
Molar mass	13885.245 g·mol

Avacincaptad pegol, sold under the brand name Izervay, is a medication used for the treatment of age-related macular degeneration. Avacincaptad pegol is a complement inhibitor.

Avacincaptad pegol was approved for medical use in the United States in August 2023.

Medical uses

Avacincaptad pegol is indicated for the treatment of geographic atrophy secondary to age-related macular degeneration.

Society and culture

Avacincaptad pegol is the international nonproprietary name.

References

^ "Izervay- avacincaptad pegol injection". DailyMed. 9 August 2023. Archived from the original on 26 August 2023. Retrieved 25 August 2023.
"Novel Drug Approvals for 2023". U.S. Food and Drug Administration (FDA). 18 August 2023. Archived from the original on 21 January 2023. Retrieved 25 August 2023. This article incorporates text from this source, which is in the public domain.
"Iveric Bio Receives U.S. FDA Approval for Izervay (avacincaptad pegol intravitreal solution), a New Treatment for Geographic Atrophy" (Press release). Astellas Pharma Inc. 4 August 2023. Archived from the original on 26 August 2023. Retrieved 25 August 2023 – via PR Newswire.
Kang C (October 2023). "Avacincaptad Pegol: First Approval". Drugs. 83 (15): 1447–1453. doi:10.1007/s40265-023-01948-8. PMID 37814173. S2CID 263801918. Archived from the original on 27 April 2024. Retrieved 18 December 2023.
"Drug Approval Package: Izervay". U.S. Food and Drug Administration (FDA). 1 September 2023. Archived from the original on 20 November 2023. Retrieved 20 November 2023.
World Health Organization (2016). "International nonproprietary names for pharmaceutical substances (INN): recommended INN: list 75". WHO Drug Information. 30 (1). hdl:10665/331046.

External links

Clinical trial number NCT02686658 for "Zimura in Participants With Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration" at ClinicalTrials.gov
Clinical trial number NCT04435366 for "A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)" at ClinicalTrials.gov