James Curran may refer to:
- James W. Curran, epidemiologist and leader of the CDC's AIDS task force during the early AIDS crisis
- James Curran (linguist), senior lecturer at the University of Sydney
- Jim Curran (1927–2005), Australian politician
- James T. Curran (1932–2015), founder of the Little Brothers of St. Francis in the Archdiocese of Boston
- James Curran (murder victim) (c. 1962–2005), victim of a politically charged murder conspiracy in Ireland
- James Michael Curran (1903–1968), American civil engineer
- James Watson Curran (1865–1920), newspaper publisher and editor
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