Jantjies is a surname. Notable people with the surname include:
- Elton Jantjies (born 1990), South African rugby union player
- Eugene Jantjies (born 1986), Namibian rugby union player
- Herschel Jantjies (born 1996), South African rugby union player
- Reggie Jantjies, South African soccer player
- Theodore Jantjies, South African actor
- Tony Jantjies (born 1992), South African rugby union player
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