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Javed Butler

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American cardiologist and researcher
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Javed Butler
BornKarachi, Pakistan
NationalityAmerican
Alma materAga Khan University
Harvard T.H. Chan School of Public Health
Emory University
Occupation(s)Cardiologist
Researcher
Organization(s)Vanderbilt University
Emory University
Stony Brook University
University of Mississippi Medical Center
American Heart Association
Known forHeart failure research, Clinical Research

Javed Butler is an American cardiologist and academic, recognized for his contributions to cardiovascular medicine, particularly in heart failure research. He serves as the Maxwell A. and Gayle H. Clampitt Endowed Chair, president, and chief research executive at Baylor Scott & White Research Institute, and senior vice president at Baylor Scott & White Health in Dallas, Texas. He is a fellow of Heart Failure Society of America, European Society of Cardiology, American College of Cardiology, and American Heart Association.

Early life and education

Born in Karachi, Pakistan, Butler completed his higher secondary education at Adamjee Science College and received his MBBS from Aga Khan University in 1990. He moved to the United States for further medical training, earning a MPH from the Harvard T.H. Chan School of Public Health in 1998 and a MBA from Emory University's Goizueta Business School in 2015.

Butler completed his residency in primary care internal medicine at Yale University, where he also served as Chief Resident. His specialization in cardiovascular disease was further developed through fellowships in Cardiovascular Disease and Heart Failure & Transplantation at Vanderbilt University. He pursued additional specialization in cardiac imaging at Massachusetts General Hospital, Harvard University.

Career

Butler began as an instructor of medicine at Yale University (1994–1995) and later served as assistant professor at Vanderbilt University (1999–2006), where he was medical director of both the Heart Transplant and heart-lung transplant programs. In 2007, he joined Emory University as a full professor of medicine and director of the Heart Failure Research Program.

At Stony Brook University, Butler served as Director of Cardiovascular Medicine and co-director of the Heart Institute (2014–2017), where he held the Charles A. Gargano Chair in Cardiology. From 2018 to 2022, he chaired the Department of Medicine at the University of Mississippi Medical Center, where he was also a professor of Physiology and Biophysics and held the Patrick H. Lehan Chair in Cardiovascular Research.

Butler has combined clinical work with research, education, and leadership, directing heart failure and transplant programs at Vanderbilt and Tennessee Valley Healthcare systems. He served as Deputy Chief Science Officer for the American Heart Association (AHA) from 2009 to 2016.

He has chaired committees for the Heart Failure Society of America and the American College of Cardiology, and represented the U.S. on the European Society of Cardiology Heart Failure Guidelines panel. Butler is a Fellow of the AHA, ACC, HFSA, and ESC.

Butler chairs the U.S. Food and Drug Administration's Cardio-Renal Advisory Committee, co-chairs the NIH-funded HeartShare study on heart failure progression, and serves as principal investigator for several international cardiovascular trials. He is ranked as one of the top cardiovascular experts globally.

Research

Butler is a heart failure expert, with research spanning prevention to advanced therapies, including cardiac transplantation and ventricular assist devices. He has led or participated in over 100 clinical trials, developed the Atlanta Cardiomyopathy Consortium, and helped establish the NIH-funded Heart Failure Network at Emory University.

Butler is an associate editor for the European Heart Journal, section editor for the Journal of the American College of Cardiology: Heart Failure, guest editor for the European Journal of Heart Failure, and serves on the editorial board of Circulation. He has also peer-reviewed for journals, including the New England Journal of Medicine, Journal of the American Medical Association (JAMA), and Lancet.

Selected publications

  • Butler, J et al. "Empagliflozin after Acute Myocardial Infarction." N Engl J Med 2024.
  • Anker SD, Butler J et al. "Empagliflozin in Heart Failure with a Preserved Ejection Fraction." N Engl J Med 2021.
  • Packer M, Butler J et al. "Empagliflozin and Major Renal Outcomes in Heart Failure." N Engl J Med 2021.
  • Butler J et al. "Semaglutide versus placebo in people with obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF DM randomised trials." Lancet 2024.
  • Armstrong PW, Butler J et al. "Effect of Vericiguat vs Placebo on Quality of Life in Patients with Heart Failure and Preserved Ejection Fraction: The VITALITY-HFpEF Randomized Clinical Trial." JAMA 2020.
  • Butler J et al. "Redefining Heart Failure with a Reduced Ejection Fraction." JAMA 2019.

References

  1. "Dr. Javed Butler's change of heart now benefits UMMC". The Clarion-Ledger.
  2. "Dr Javed Butler Explains How Finerenone Is Shaping New Treatment Standards for HF". The American Journal of Managed Care. 5 September 2024.
  3. "Javed Butler". Food and Drug Administration.
  4. "Web of Science gives Medicine chair highly cited distinction; MLS student earns national scholarship". University of Mississippi Medical Center.
  5. "Javed Butler". Baim Institute for Clinical Research.
  6. "Co-Director of Stony Brook Heart Institute Elected to Association of University Cardiologists - SBU News". Stony Brook University. 29 September 2015.
  7. "Javed Butler, MD: A nationally recognized HF investigator". healio.
  8. "Javed Butler". Cardiometabolic Health Congress.
  9. "Expert in Heart Failure Named Co-Director of Heart Institute - SBU News". Stony Brook University. 24 October 2014.
  10. "Professor Javed Butler". esc365.escardio.org.
  11. "UTSW cardiologists recognized for mentorship, research - CT Plus - UT Southwestern". UT Southwestern Medical Center.
  12. "Featured Alumnus: Dr. Javed Butler, AKU '90". Aga Khan University Alumni Association of North America. 18 April 2012.
  13. "Advancing the Field of Valve Interventions for Mitral and Tricuspid Regurgitation". The American Journal of Managed Care. 30 September 2024.
  14. "Medicine gains 'Grade A mentor, human being' as new department chair". University of Mississippi Medical Center.
  15. "Javed Butler MD, MPH". National Forum for Heart Disease & Stroke Prevention. 19 December 2017.
  16. "PRIME® Faculty Biography - Javed Butler, MD, MPH, MBA". primeinc.org.
  17. "Dr. Javed Butler: Making an Impact". University of Mississippi Medical Center. 6 May 2024.
  18. "Javed Butler, MD: Promising Heart Failure Trials and Guideline Limitations". HCP Live. 13 September 2021.
  19. "Javed Butler, MD, PhD | Renaissance School of Medicine at Stony Brook University". renaissance.stonybrookmedicine.edu.
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