Joe Louis (1914–1981) was an American world heavyweight boxing champion.
Joe Louis may also refer to:
- Joe Louis (puppeteer) (Sakorn Yang-keawsot, 1922–2007), Thai dancer and puppeteer
- Joe Louis (horse), a horse owned by the United States Army
- Joe Hill Louis (1921–1957), American musician
See also
- Joe Louis Arena in Detroit
- Jos Louis, chocolate pastry
- Joe Lewis (disambiguation)
- Joseph Lewis (disambiguation)
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