John Houghton may refer to:
Politicians
- John Houghton (fl.1393), MP for Leicester (UK Parliament constituency)
- John Houghton (died 1583) (before 1522–1583), MP for Stamford (UK Parliament constituency)
- John Houghton (Manx politician)
- John Houghton (Zimbabwean politician)
Others
- John Houghton (physicist) (1931–2020), Welsh atmospheric physicist
- John Houghton (martyr) (c. 1486–1535), English Catholic priest and martyr
- John Houghton (apothecary) (1645–1705), English writer, apothecary and merchant
- John Houghton (footballer), New Zealand international footballer
- John Houghton (footballer born 1891) (1891–1991), English footballer
- John Houghton (rugby league) (fl. 1970), former St Helens RLFC rugby player
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