Johne is both a surname and a given name. Notable people with the name include:
- Surname
- Heinrich Albert Johne (1839–1910), German pathologist
- Nick Johne (born 1955), Canadian actor
- Karol de Johne (1890–1949), Polish literary critic
- Given name
- Johne Murphy (born 1984), Irish rugby player
- Johne Rotz, 16th-century French artist-cartographer
- Johne Binkley (born 1953), politician in Alaska, USA
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